Two formats to enable children and adolescents to report the changing intensity, duration, and pattern of their pain were developed and tested: (a) a dot matrix with intensity markers on the y-axis and time markers on the x-axis and (b) a list of words or word phrases describing the temporal dimension of pain. Analyses of the dot matrix markings revealed six patterns of pain: steady decrease, steady increase, ongoing sharp increases and decreases, stair-step increase and decrease, steady increase and decrease, and constant. The 12 words and phrases described how pain began as well as how the pattern of pain changed over time.
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Psychotic disorders, such as schizophrenia and bipolar disorder, pose significant diagnostic challenges with major implications on mental health. The measures of resting-state fMRI spatiotemporal complexity offer a powerful tool for identifying irregularities in brain activity. To capture global brain connectivity, we employed information-theoretic metrics, overcoming the limitations of pairwise correlation analysis approaches.
View Article and Find Full Text PDFTau exhibits change in both spatial extent and density of pathology along the Alzheimer's disease (AD) spectrum with each aspect contributing to the overall burden of pathological tau. Nevertheless, studies using Tau PET have measured either magnitude using standardized uptake value ratios (SUVRs) or extent using number of Tau+ regions. We hypothesized that combining these two dimensions into a single measure of Magnitude and eXtent, Tau-MaX, would provide improved quantification of global tau burden as well as allowing for a region-agnostic measure of global tau burden that does not require a pre-specified region of interest (ROI) or meta-ROI.
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Front Psychiatry
January 2025
Faculty of Psychology and Educational Sciences, University of Geneva, Geneva, Switzerland.
Introduction: While functional neuroimaging studies have reported on the neural correlates of severe antisocial behaviors, such as delinquency, little is known about whole brain resting state functional connectivity (FC) of incarcerated adolescents (IA). The aim of the present study is to identify potential differences in resting state connectivity between a group of male IA, compared to community adolescents (CA). The second objective is to investigate the relations among FC and psychological factors associated with delinquent behaviors, namely psychopathic traits (callous unemotional traits, interpersonal problems, and impulsivity), socio-cognitive (empathy and reflective functioning RF) impairments and psychological problems (externalizing, internalizing, attention and thought problems).
View Article and Find Full Text PDFCan fundus features tell us something about 3D eye shape?
Ophthalmic Physiol Opt
January 2025
Robert O Curle Ophthalmology Suite, Institute for Regeneration and Repair, The University of Edinburgh, Edinburgh, UK.
Purpose: To determine whether imaging features derived from fundus photographs contain 3D eye shape information beyond that available from spherical equivalent refraction (SER).
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Pitch-based correspondences related to abstract concepts.
Acta Psychol (Amst)
January 2025
Phonetics and speech synthesis research group, Department of Digital Humanities, Faculty of Arts, University of Helsinki, Unioninkatu 38, Helsinki, Finland. Electronic address:
Previous investigations have shown pitch-based correspondences with various perceptual and conceptual attributes. The present study reveals two novel pitch-based correspondences with highly abstract concepts. Three experiments with varying levels of implicitness of the association task showed that the concepts of future and in are associated with high-pitch sounds, while past and out are associated with low-pitch sounds.
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