The purpose of this project was to evaluate magnetic resonance imaging (MRI) accuracy for diagnosing and defining meniscal pathology. The charts of 45 patients who underwent both MRI and arthroscopy were viewed retrospectively. All cases were seen by one of two orthopedic surgeons. Magnetic resonance imaging scans were reviewed by staff radiologists at the University of Michigan Hospital Medical Center. Arthroscopy was used as the standard for comparing MRI results. Data were analyzed two ways with respect to questionable (code 3) MRI lesions. First, all code 3 lesions were interpreted as either true positives or negatives. Second, all code 3 lesions that corresponded with a negative arthroscopy finding were interpreted as false positives. The MRI accuracy was 87.8% when considering nonmatching code 3 lesions as true positives or negatives. The accuracy declined to 82.2% when considering code 3 lesions as false negatives. Magnetic resonance imaging sensitivity for medial meniscal and lateral meniscal tears was 84.6% and 87.5%, respectively, regardless of code 3 interpretation. The specificity for medial meniscal tears with and without the negative effect was 71.9% and 84.4%, respectively. The specificity with and without considering code 3 lesions as false positives was 89.2%, and 91.9%, respectively.
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Int Heart J
January 2025
Department of Cardiology, Kameda Medical Center.
Current classifications of chronic limb-threatening ischemia (CLTI) are insufficient to identify Rutherford (R) 4 patients with a poor prognosis. This study aimed to investigate the prognostic factors for patients with R4 CLTI who undergo endovascular treatment (EVT) using data from the Tokyo-taMA peripheral vascular intervention research COmraDE (TOMA-CODE) registry and to propose a risk-scoring system. We analyzed the data of 2,248 prospectively enrolled patients from the registry, divided into 3 groups: intermittent claudication (IC), n = 1,185; R4, n = 401; and R5-6, n = 662.
View Article and Find Full Text PDFArthritis Res Ther
January 2025
Division of Rheumatology and Immunology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, Graz, 8036, Austria.
Background: Axial spondyloarthritis (SpA) leads to structural bone lesions in every part of the vertebral column. These lesions are only partially visualized on conventional radiographs, omitting posterior parts of the vertebral column and the thoracic spine, that may nevertheless contribute to impaired spinal mobility and function in patients with axial SpA.
Methods: In this prospective and blinded investigation, we assessed the distribution of structural spinal lesions using magnetic resonance imaging (MRI) of the whole spine in 55 patients with axial SpA classified according to the Assessment in Spondyloarthritis International Society (ASAS) criteria.
Zhongguo Zhong Yao Za Zhi
December 2024
State Key Laboratory of Traditional Chinese Medicine Syndrome, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine Guangzhou 510120, China.
The study explored the pathological mechanism of doxorubicin chemotherapy-induced neurotoxicity and the intervention methods of traditional Chinese medicine. BALB/c mice were selected to establish tumor-bearing mouse models by orthotopic injection of 4T1 triple-negative breast cancer cells. After randomization, the mice were treated with doxorubicin chemotherapy or doxorubicin chemotherapy + Kaixin San(KXS).
View Article and Find Full Text PDFJ Foot Ankle Surg
January 2025
University of Rochester Department of Orthopaedic Surgery, 601 Elmwood Ave, Rochester, NY 14642.
Tarsal tunnel syndrome is an entrapment neuropathy of the tibial nerve and its branches in the tarsal tunnel. The literature on surgical release of the tarsal tunnel shows variable outcomes with no studies reporting validated patient reported outcomes. We aim to determine clinical response after tarsal tunnel release using the Patient-Reported Outcomes Measurement Information System (PROMIS).
View Article and Find Full Text PDFBMC Vet Res
January 2025
Department of Parasitology, Faculty of Veterinary Medicine, Cairo University, Giza, 12211, Egypt.
This study aimed to evaluate alternative in vivo treatment trials using natural products for ectoparasitic infestation on Nile tilapia; these two products were not previously used in the treatment of parasitic fish diseases. So, a total of 400 Oreochromis niloticus (O. niloticus) fish measured 10-15 cm in length; 350 from a fish farm in (Kafr Elsheikh and 50 from Nile River (Al Bahr Al Aazam), Egypt.
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