AI Article Synopsis
- Chloroform and ethyl ether treatment of sera led to a notable reduction in the phagocytic activity of PMN leucocytes against C. albicans.
- In particular, chloroform-treated sera showed an increased ability to inhibit phagocytosis compared to ethyl ether, with decreases in activity of about 63% and 45%, respectively.
- Additionally, both treatments significantly reduced the candidacidal capacity and NBT reduction capability, with chloroform causing a 66% decrease and ethyl ether causing a 42% decrease.
Article Abstract
The opsonization of C. albicans by means of sera treated with chloroform and ethyl ether resulted in significantly decreased values of PMN leucocyte phagocytic activity. In contrast to ethyl ether treated sera (decrease of phagocytic activity about 45%), chloroform processed sera possessed increased antiphagocytic activity (decrease of phagocytic activity about 63%). Significant changes were observed in the candidacidal capacity to C. albicans (decrease about 50%) and in the capacity of NBT (INT) reduction measured spectrophotometrically (decrease about 66% in chloroform treated sera and about 42% in ethyl ether treated sera). (Fig. 1, Ref. 22.)
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