The vaccination of young piglets, with or without passive antibodies of colostral origin, was studied using the Thiverval strain. The various experiments, carried out under practical conditions, allowed us to observe the following phenomena:--in piglets without immunity of maternal origin we observed a classic primary reaction, with vigourous, lasting production of antibodies and resistance to the challenge;--in piglets with immunity of maternal origin, depending on when the vaccination was administered, the production of primary antibodies was non-existent or deficient; however, we noted that piglets vaccinated 35 days after birth resist the challenge.

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