In this paper the autoimmune eye disease complex is presented in detail. The problems of autoagressivity in the light of new conceptions based on modern microchemical, chemical and immunological methods of analysis that allow better insight in the nature of these diseases are discussed. The basic concepts of immunological mechanisms and autoimmunity are explained, with special attention given to those occurring in the eye. Attention is directed towards the importance of various intra- and extraocular factors, as well as to the regulatory mechanisms that influence the autoimmune eye disease's development. In the conclusion the authors analyze the abilities and aims of further investigations of this field of ophthalmoimmunopathology.
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