The influences of the static whole body roll tilts (30 or 45 degrees) on horizontal optokinetic nystagmus (HOKN) produced by optokinetic stimuli at a constant velocity (16 or 30 degrees/sec) were examined in the 16 pigeons. The significant tilt-dependent asymmetry of the tonic otolith effects on optokinetic system was revealed which consists in pronounced inhibitory effect of the right-hand tilts unlike the left-hand tilts on HOKN. Separate recording of the oculomotor responses from the right and left eyes showed that during static roll tilts the temporonasal-nasotemporal (TN-NT) asymmetry of HOKN normally existing in the pigeon remained for the eye disposed above and was replaced by symmetric pattern for the eye disposed below. The results suggest the mechanism of TN-NT asymmetry is controlled by the otolith inputs and its function can be essentially modified under the influence of otolith membranes reorientation in gravity.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Characterization of Optokinetic Nystagmus in Healthy Participants With a Novel Oculography Device.
Otolaryngol Head Neck Surg
January 2025
Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, USA.
Objective: To develop a proof-of-concept smart-phone-based eye-tracking algorithm to assess non-pathologic optokinetic (OKN) nystagmus in healthy participants. Current videonystagmography (VNG) is typically restricted to in-office use, and advances in portable vestibular diagnostics would yield immense public health benefits.
Study Design: Prospective cohort study.
The vestibular and oculomotor dysfunction in Fabry disease: a cohort study in China.
Ann Med
December 2025
Department of Neurology, Peking University First Hospital, China.
Objective: Whereas a few studies have evaluated vestibular involvement in Fabry disease (FD), the relationship between vestibular/oculomotor abnormalities and disease-specific biomarkers remain unclear. Therefore, we seek to evaluate these quantitatively and analyze their relationship with disease phenotype and biomarkers in FD.
Methods: This cohort study enrolled 37 Chinese FD patients registered in our center.
Optokinetic After-Nystagmus: A Marker for Migraine? A Prospective Observational Study.
J Otolaryngol Head Neck Surg
January 2025
Département d'ORL du CHUS, Université de Sherbrooke, Sherbrooke, Quebec, Canada.
Introduction: Vestibular migraine (VM), particularly its chronic variant, poses a diagnostic challenge. Patients suffering from VM may not have the characteristic headaches associated with the dizziness. In these cases, a marker for migraine pathology in general could help appropriately diagnose certain types of dizziness as migrainous despite these patients not meeting current diagnostic criteria for VM.
View Article and Find Full Text PDFNormative Ranges for Oculomotor and Reaction Time Tests in U.S. Military Service Members and Veterans.
J Am Acad Audiol
May 2024
Audiology and Speech Pathology Center, Walter Reed National Military Medical Center, Bethesda, Maryland.
Background: Oculomotor and reaction time tests are frequently used assessments of vestibular symptoms, traumatic brain injury (TBI), or other neurological disorders in both clinical and research contexts. When interpreting these tests it is important to have a reference interval (RI) as a comparison for what constitutes a typical/expected response; however, the current body of research has only limited information regarding normative ranges calculated according to established standards or for a military-specific sample.
Purpose: The purpose of the present study was to describe RIs for oculomotor and reaction time tests in a cohort of service members and veterans (SMVs) for use as comparators by clinicians and scientists.
Association Between Noise-Induced Hearing Loss and Vestibular Dysfunction in Workers Chronically Exposed to Occupational Noise.
Indian J Occup Environ Med
September 2024
Department of Occupational Health and Safety, Shoushtar Faculty of Medical Sciences, Shoushtar, Iran.
Background: Despite the understanding of the association between noise exposure and noise-induced hearing loss (NIHL), the effects of noise on vestibular function are less well understood and neglected.
Aim: The aim of this study was to investigate the function of the vestibular system in workers with NIHL.
Materials And Methods: Thirty male textile workers with symmetrical NIHL (49.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!