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Motor functional hierarchical organization of cerebrum and its underlying genetic architecture in Parkinson's disease.
J Neurosci
January 2025
department of radiology, the first hospital of China medical University, Shenyang,110001, China
Hierarchy has been identified as a principle underlying the organization of human brain networks. However, it remains unclear how the network hierarchy is disrupted in Parkinson's disease (PD) motor symptoms and, how it is modulated by the underlying genetic architecture. The aim of this study was to explore alterations in the motor functional hierarchical organization of the cerebrum and their underlying genetic mechanism.
View Article and Find Full Text PDFAllowed response time and estimated average body size influence visual body size estimates.
Acta Psychol (Amst)
January 2025
Department of Experimental Psychology, Faculty of Social and Behavioural Sciences, Utrecht University, Utrecht, the Netherlands. Electronic address:
Studies show that body size estimates exhibit a contraction bias wherein participants with a lower-than-average BMI overestimate their bodies while participants with a higher-than-average BMI underestimate. We attempted to replicate this effect and test its relationship to allowed response time and estimates of average body size. Neurotypical female Dutch participants (n = 277) estimated their body size using a forced-choice task, which we modified to modulate allowed response time, and a method-of-adjustment task.
View Article and Find Full Text PDFUtilizing Tissues Self-Assembled in Fiber Optic-Based "Chinese Guzheng Strings" for Contractility Sensing and Drug Efficacy Evaluation: A Practical Approach.
Small
January 2025
State Key Laboratory of Biocatalysis and Enzyme Engineering, Stem Cells and Tissue Engineering Manufacture Center, School of Life Science, Hubei University, Wuhan, Hubei, 430062, China.
Recent advances in drug design and compound synthesis have highlighted the increasing need for effective methods of toxicity evaluation. A specialized force sensor, known as the light wavelength-encoded "Chinese guzheng" is developed. This innovative sensor is equipped with optical fiber strings and utilizes a wavelength-encoded fiber Bragg grating (FBG) that is chemically etched to reduce its diameter.
View Article and Find Full Text PDFImaging-based method to quantify left ventricular diastolic pressures.
Eur Heart J Cardiovasc Imaging
January 2025
School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Aim: To establish an imaging-based method to quantify left ventricular (LV) diastolic pressures.
Methods/results: In 115 patients suspected of coronary artery disease, LV pressure was measured by micromanometers and images by echocardiography. LV filling pressure was measured as LV pre-atrial contraction pressure (pre-A PLV).
Exploiting photopolymerization to modulate liquid crystalline network actuation.
Soft Matter
January 2025
LENS (European Laboratory for Non-Linear Spectroscopy) Via Nello Carrara 1, 50019 Sesto Fiorentino (FI), Italy.
Liquid Crystalline Networks (LCNs) are widely investigated to develop actuators, from soft robots to artificial muscles. Indeed, they can produce forces and movements in response to a plethora of external stimuli, showing kinetics up to the millisecond time-scale. One of the most explored preparation technique involves the photopolymerization of an aligned layer of reactive mesogens.
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