AI Article Synopsis
- The article discusses the long-term effects experienced by childhood cancer survivors after successful treatment, with a focus on complications from radiation therapy.
- It highlights that both radiation and chemotherapy can lead to significant biological and psychological issues, such as sterility and other health complications that may not be immediately apparent.
- It emphasizes the need for continuous monitoring and regular radiographic studies to catch these complications early and improve the quality of life for survivors.
Article Abstract
This article has provided an account of the delayed effects after successful treatment for childhood cancer. Particular emphasis has been placed on sequelae induced by radiation therapy. Chemotherapy-related complications that may simulate or aggravate these sequelae also are recorded. The alterations induced by radiation therapy and chemotherapy are not limited to the organs and tissues described in this article. Subtle, and at times psychologically devastating, sequelae also may be encountered (eg, sterility due to radiation and chemotherapeutic effects on the gonads). However, an attempt has been made only to identify those complications that may be more readily detected by means of radiographic studies. It is recommended that ongoing surveillance of the long-term successfully treated childhood cancer survivor be conducted in order to detect such complications. Early detection will assist in implementing appropriate treatment, minimizing delayed effects, and maximizing the quality of life. Periodic radiographic studies of previously radiated areas at regular intervals therefore appears appropriate.
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| http://dx.doi.org/10.1016/s0037-198x(05)80068-9 | DOI Listing |
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