The effects of midodrine hydrochloride (Brand name: Metligine tablet 2 mg, Manufacturer: Taisho Pharmaceutical Co., Ltd.), alpha-1 adrenalin receptor agonist against urinary incontinence was examined on 5 female patients with stress urinary incontinence and 5 male urinary incontinent patients of various causes. Metligine was administered in the dose of 4 mg daily for 2 to 4 weeks. Eighty per cent of the stress incontinent patients showed improvement and five incontinent male also showed improvement of symptoms. No side effects were recognized.

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