The efficacy and tolerability of nimesulide were assessed and compared with those of paracetamol in the treatment of 35 children with pain and inflammation following adenotonsillectomy. The antipyretic and analgesic efficacy of the 2 drugs was similar, although more patients had complete remission of pain after 4 days of treatment with nimesulide. Both drugs were well tolerated, even though occasional elevation of transaminase enzymes and alkaline phosphatase was noted in the nimesulide-treated group. It is postulated that this effect may have been attributable to the volatile anaesthetics used during surgery.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.2165/00003495-199300461-00060 | DOI Listing |
Publication Analysis
Top Keywords
efficacy tolerability
8
tolerability nimesulide
8
assessment efficacy
4
nimesulide paracetamol
4
paracetamol children
4
children adenotonsillectomy
4
adenotonsillectomy efficacy
4
nimesulide assessed
4
assessed compared
4
compared paracetamol
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!