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Therapeutic Potential of Menstrual Blood-Derived Stem Cells in Attenuating Uterine Adhesion: Novel Strategies and Future Prospect.
Curr Pharm Des
January 2025
Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Intrauterine Adhesions (IUAs) are characterized by endometrial damage due to endometritis or curettage. Currently, the gold standard for IUA treatment is hysteroscopy, which enables the dissolution of IUA through mechanical or electrosurgical energy. Common strategies to prevent recurrence include the insertion of a balloon catheter or IUD in the uterus.
View Article and Find Full Text PDFCold scissors ploughing technique versus electrosurgical excision for hysteroscopic adhesiolysis: a multicenter randomized controlled trial.
Int J Surg
December 2024
Medical Integration and Practice Center, Shandong University, Jinan, China.
Intrauterine adhesions (IUA) may lead to abnormal menstruation, infertility, and pregnancy-related complications. Hysteroscopic separation is the gold standard treatment for IUA and can be performed using a variety of instruments and methods, including cold scissors and electrotomy. However, it is unclear which method is more effective for relieving IUA, restoring uterine anatomy, and improving the pregnancy rate in women of childbearing age.
View Article and Find Full Text PDFEvaluation of Pain During Hysteroscopy Under Local Anesthesia, Including the Stages of the Procedure.
J Clin Med
November 2024
Department of Maternal and Child Health and Minimally Invasive Surgery, Poznan University of Medical Sciences, 60-701 Poznan, Poland.
Hysteroscopy is an endoscopic diagnostic and therapeutic method traditionally performed under general anesthesia but increasingly under local anesthesia. Today, it is considered the gold standard in gynecology. This minimally invasive procedure allows for a detailed assessment of the uterine cavity's interior and the removal of abnormal changes within it and is applicable to patients of all ages.
View Article and Find Full Text PDFMechanistic insights into intrauterine adhesions.
Semin Immunopathol
November 2024
Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Article Synopsis
- Intrauterine adhesions (IUA), also known as Asherman's syndrome, occur due to damage to the endometrial layer, often from medical procedures, leading to fibrous tissue formation that can block the uterine cavity or cervical canal.
- Diagnosis of IUA is best performed through hysteroscopy, but predicting future live birth rates remains uncertain.
- New research on the underlying causes of IUA, including inflammation, cellular balance issues, autophagy defects, and ferroptosis, is essential for developing improved treatment strategies.
Novel Minimally Invasive Surgical Approaches to Endometriosis and Adenomyosis: A Comprehensive Review.
J Clin Med
November 2024
Department of Gynecology, Minimally Invasive Gynecological Surgery Unit, Unidade Local de Saúde de Santo António, 4050-342 Porto, Portugal.
Endometriosis and adenomyosis are chronic gynecological conditions that significantly impact women's quality of life, leading to symptoms such as pelvic pain, dysmenorrhea, and infertility. Despite ongoing research, a definitive cure for these conditions remains elusive, and treatment often focuses on managing symptoms. Minimally invasive surgery is considered the gold standard for surgical management, but novel surgical techniques are continuously being developed to enhance outcomes.
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