The restriction endonuclease profiles of DNAs from Helicobacter pylori strains isolated from 20 patients in two or more consecutive biopsy specimens over a period of up to 2 years were analyzed by pulsed-field gel electrophoresis with NotI and NruI. H. pylori strains possess a high degree of genomic diversity which was not observed to occur in vivo, and attempts to observe it in vitro were not successful.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC228454 | PMC |
| http://dx.doi.org/10.1128/jcm.33.9.2496-2497.1995 | DOI Listing |
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