Studies made in 54 patients and "in vitro" experiment permitted finding out that insulin exerts major effect on the blood neutrophil functional status. It activates phagocytizing function of leucocytes as a result of intensification of glycolysis and cellular respiration, favours intracellular plastic processes. Elimination of hyperglycemia, insulin deficiency are prerequisites of success in correction of disturbances in phagocytizing function of cells in patients with diabetes mellitus.

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