Failures and complications are analysed from experience in 325 operations of laparoscopic cholecystectomy. Change to laparotomy was undertaken in 5 (1.5%) patients. The total amount of complications was 45.2%, among them 36.5% were intraoperative and 8.7% postoperative, but only 3.8% were hazardous for the patients. Mortality was 0.3% (one patient dies from cardiovascular failure). A classification of complications and the technical principles of the operation are discussed.
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January 2025
School of Mathematics and Physics, Qingdao University of Science and Technology, Qingdao 266061, China; Qingdao Innovation Center of Artificial Intelligence Ocean Technology, Qingdao 266061, China; The Research Institute for Mathematics and Interdisciplinary Sciences, Qingdao University of Science and Technology, Qingdao 266061, China. Electronic address:
This paper considers the event-triggered adaptive fault-tolerant control (FTC) problem for a class of stochastic nonlinear systems suffering from finite number of actuator failures and abrupt system external failure. Unlike existing event-triggered mechanisms (ETMs), this paper proposes an improved switching threshold mechanism (STM) that effectively addresses the potential system security hazards caused by large signal impulses when both the magnitude size of the controller and its rate of change are too large, while also saving energy consumption. Especially, when the occurrence of both actuator failure and system external failure may lead to over-change rate of the controller, by using the multi-dimensional Taylor network (MTN) approximation technique, the adaptive fault-tolerant control scheme designed based on the improved STM not only has lower resource consumption, but also indirectly improves the control performance of the system by ensuring the system security operation.
View Article and Find Full Text PDFRadiographics
February 2025
From the Department of Radiology, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA 02215.
Nonpregnant and pregnant women who present with acute pelvic pain can pose a diagnostic challenge in the emergency setting. The clinical presentation is often nonspecific, and the differential diagnosis may be very broad. These symptoms are often indications for pelvic US, which is the primary imaging modality when an obstetric or gynecologic cause is suspected.
View Article and Find Full Text PDFFront Immunol
January 2025
Cell Therapy and Hematopoietic Stem Cell Transplantation Research Center, Research Institute for Oncology, Hematology and Cell Therapy, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Background: With recent advances in clinical practice, including the use of reduced-toxicity conditioning regimens and innovative approaches such as ex vivo TCRαβ/CD19 depletion of haploidentical donor stem cells or post-transplant cyclophosphamide (PTCY), hematopoietic stem cell transplantation (HSCT) has emerged as a curative treatment option for a growing population of patients with inborn errors of immunity (IEI). However, despite these promising developments, graft failure (GF) remains a significant concern associated with HSCT in these patients. Although a second HSCT is the only established salvage therapy for patients who experience GF, there are no uniform, standardized strategies for performing these second transplants.
View Article and Find Full Text PDFFront Med (Lausanne)
January 2025
College of Medicine, Chungbuk National University, Cheongju, Republic of Korea.
Introduction: Sepsis, a life-threatening condition with a high mortality rate, requires intensive care unit (ICU) admission. The increasing hospitalization rate for patients with sepsis has escalated medical costs due to the strain on ICU resources. Efficient management of ICU resources is critical to addressing this challenge.
View Article and Find Full Text PDFCirculation
January 2025
Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (Y.N.V.R., A.T., M.M.R., B.A.B.).
Background: Plasma NT-proBNP (N-terminal pro-B-type natriuretic peptide) is commonly used to diagnose heart failure with preserved ejection fraction (HFpEF), but its diagnostic performance in the ambulatory/outpatient setting is unknown because previous studies lacked objective reference standards.
Methods: Among patients with chronic dyspnea, diagnosis of HFpEF or noncardiac dyspnea was determined conclusively by exercise catheterization in a derivation cohort (n=414), multicenter validation cohort 1 (n=560), validation cohort 2 (n=207), and a nonobese Japanese validation cohort 3 (n=77). Optimal NT-proBNP cut points for HFpEF rule out (optimizing sensitivity) and rule in (optimizing specificity) were derived and tested, stratified by obesity and atrial fibrillation.
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