The authors present the development of a generalized necrotic vasculitis accompanied by positive Virus B Cronic Hepatitis. A 31 years old female, affected by a multisystemic disease with jaundice, dark urine, and light stools, with biologic values of necrosis of hepatic cells and positive dosages of HBsAg. The biopsy of muscle revealed the presence of an alergic vasculitis with leucocitoclasia and the biopsy of the liver showed and Active Cronic Hepatitis. References are made about the different pathogenical hypothesis of these unusual association.
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