Patients with advanced breast cancer and low or poor concentration of estrogen receptors in tumor biopsies have little chance of responding to endocrine therapy. This problem was seen in a group of nonresponding estrogen receptor-positive (ER+) patients. Some comments on possible explanations for this phenomenon are made and suggestions to overcome it are given.
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| http://dx.doi.org/10.1002/1097-0142(19801215)46:12+<2835::aid-cncr2820461420>3.0.co;2-m | DOI Listing |
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