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Association of dysautonomia and different risk factors in patients with Guillain-Barré syndrome in a tertiary hospital in the Philippines.
BMC Neurol
January 2025
Department of Neurosciences, College of Medicine and Philippine General Hospital, University of the Philippines Manila, Manila, Philippines.
Background: Guillain-Barré syndrome (GBS) presents with progressive ascending weakness, but it can also present with dysautonomia such as tachycardia, blood pressure fluctuations, diaphoresis, ileus, and urinary retention. GBS patients with dysautonomia was observed to have longer hospital stays and higher mortality rates than those without dysautonomia. We aimed to determine the risk factors for dysautonomia and its manifestations among patients with GBS and compared their features to those without dysautonomia.
View Article and Find Full Text PDFMycoplasma pneumoniae-Triggered Guillain-Barré Syndrome in Children: Two Case Reports of Different ICU Presentations.
Cureus
November 2024
Pediatric Neurology, King Fahad Medical City, Riyadh, SAU.
Guillain-Barré syndrome (GBS) is an acute immune-mediated polyneuropathy with diverse clinical presentations. Mycoplasma pneumoniae has been increasingly recognized as a potential trigger, particularly in pediatric cases. This case report presents two atypical cases of M.
View Article and Find Full Text PDFResolution of acute motor axonal neuropathy in a patient after treatment with efgartigimod: A case report.
Medicine (Baltimore)
December 2024
Department of Neurology, The First Affiliated Hospital, Zhejiang University, Medical School, Hangzhou, China.
Background: Guillain-Barré syndrome (GBS) is an acute autoimmune neuropathy characterized by progressive muscle weakness, often caused by immunoglobulin G (IgG) autoantibodies. There are several subtypes of GBS, of which acute motor axonal neuropathy (AMAN) is one of the most severe subtypes associated with axonal damage. It is well known that the current clinical standard of treatment is intravenous immunoglobulin (IVIg) and plasma exchange (PLEX), but some patients often show limited response or experience persistent disability.
View Article and Find Full Text PDFGuillain-Barrè syndrome after treatment with anti-tumour necrosis factor α (etanercept) in a rheumatoid arthritis patient: Case report and literature review.
Sci Prog
December 2024
College of Medicine and Health Science, Palestine Polytechnic University, Hebron, State of Palestine.
Rheumatoid arthritis (RA) is often treated with anti-tumor necrosis factor α (anti-TNF-α) medications. While these drugs can cause common side effects such as injection-site and infusion reactions, rare cases of Guillain-Barré syndrome (GBS) have been reported. It's a potentially life-threatening condition characterized by progressive, ascending weakness of the extremities and areflexia, with an incidence of about 1.
View Article and Find Full Text PDFFatal ascending paralysis after typhoid vaccine: Guillain and Barré's description of the very first case.
Vaccine
December 2024
Professor of Neurology and the History of Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905., United States. Electronic address:
Article Synopsis
- - The study revisits the historical context of Guillain-Barré syndrome (GBS) linked to vaccines, focusing on the first case documented during WWI related to a typhoid vaccine.
- - A detailed review of a case involving a 31-year-old brigadier revealed that after receiving a typhoid vaccine, he quickly experienced severe muscle weakness leading to respiratory failure, with specific findings in his cerebrospinal fluid.
- - The case marks the earliest instance of vaccine-associated GBS, highlighting the association, albeit rare, between vaccines and this neurological condition.
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