An inaugural pericardiac tamponade performed on a 39 years old man, reveals a lympho-epithelial thymoma. The anatomic diagnosis first suggested by the radiography after evacuation of the effusion, is confirmed by the swab taken during the retroxiphoidal drainage. A 57 Gray cobaltotherapy was then performed. 18 months later, a satisfactory general state, allowed the patient to return to his professional activity. The evaluation of a tumourous residue by a tomodensitometry, is discussed at the light of a comparable observation confirming the efficiency of cobaltotherapy but, at the same time, its agressivity for such an important target volume. A previous surgical reduction, whenever possible, is then considered; an unthinkable eventuality in the reported observation.
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J Craniomaxillofac Surg
January 2013
UOC Maxillo-Facial Surgery, Santo Spirito Hospital, Lungotevere in Sassia 1, Roma 00193 [corrected] Italy.
The ectopic cervical thymoma is a rare site for a thymus neoplasm. It is frequently confused with cyst or with later neck mass of uncertain diagnosis until a histological diagnosis is made. Thymic neoplasms normally arise in the mediastinum, causing signs and symptoms of compression of the adjacent structures.
View Article and Find Full Text PDFArch Mal Coeur Vaiss
June 2005
Unité de soins cardiaques intensifs, service de cardiologie A.
The authors report the case of a 62 year old patient admitted for a tamponade, revealing a mixed lympho-epithelial thymoma with invasion of the pericardium, the aorta and of the pulmonary arteria. The histological diagnosis was confirmed by a surgical biopsy performed after emergency pericardiocentesis. A neoadjuvant chemotherapy was administered followed by incomplete surgical resection and then a post operative radiotherapy.
View Article and Find Full Text PDFRev Pneumol Clin
September 2003
Service de Médecine Interne, Centre Hospitalier Intercommunal de Meulan-Les Mureaux, 1, rue du Fort, 78250 Meulan.
We report an association between a thymus tumor and autoimmune thyroiditis. This association is probably related to loss of immune control secondary to loss of thymus integrity. A 48-year-old woman was hospitalized for thoracic pain.
View Article and Find Full Text PDFNihon Kokyuki Gakkai Zasshi
March 2000
Department of Surgery I, Tokyo Women's Medical University.
We encountered two cases of thymoma accompanied by pure red cell aplasia and demonstrating clonal rearrangement of the T-cell receptor beta-chain gene (TCR-beta) in lymphocytes. Patient 1 was a 55-year-old man and Patient 2 was a 43-year-old woman. Both had severe anemia and mediastinal tumors.
View Article and Find Full Text PDFOncogene
January 2000
Herman B Wells Center for Pediatric Research Indiana University School of Medicine, Riley Hospital, 702 Barnhill Drive, Room 2600, Indianapolis, Indiana, IN 46202-5225, USA.
Thymoma is the most common tumor of the anterior-superior mediastinum. We have identified a line of transgenic mice which spontaneously and heritably develop thymomas at a very high penetrance. The available data suggest that thymoma formation in these mice results as a consequence of transgene insertional mutagenesis.
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