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Influence of Sorbitol and Glycerol on Physical and Tensile Properties of Biodegradable-Edible Film From Snakehead Gelatin and -Carrageenan.
Int J Food Sci
January 2025
Institute of Microengineering and Nanoelectronics, Universiti Kebangsaan Malaysia, Bangi, Malaysia.
Two plasticizers with distinct properties are carefully studied in this research for their suitability in creating biocomposite edible film products. The study uncovers films' physical, tensile, and biodegradability attributes, using snakehead gelatin and ĸ-carrageenan in different concentrations, with sorbitol or glycerol as plasticizers. The biomaterials of the edible film consist of snakehead gelatin () 2% (/); ĸ-carrageenan at concentrations of 1%, 1.
View Article and Find Full Text PDFCriterion validity of five open-source app-based cognitive and sensory tasks in an Australian adult life course sample aged 18 to 82: Labs without walls.
Behav Res Methods
January 2025
School of Psychology, University of New South Wales, Sydney, Australia.
With recent technical advances, many cognitive and sensory tasks have been adapted for smartphone testing. This study aimed to assess the criterion validity of a subset of self-administered, open-source app-based cognitive and sensory tasks by comparing test performance to lab-based alternatives. An in-person baseline was completed by 43 participants (aged 21 to 82) from the larger Labs without Walls project (Brady et al.
View Article and Find Full Text PDFDesign, Preparation, and Ex Vivo Skin Permeation of Doxepin Microemulsion System for Topical Delivery.
J Cosmet Dermatol
January 2025
Department of Pharmaceutics, Faculty of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Background: Doxepin (DX) is used orally to relieve itching but can cause side effects like blurred vision, dry mouth, and drowsiness due to its antimuscarinic effect. To reduce these adverse effects and improve skin permeation, DX is being developed in topical formulations. This study aims to improve DX skin absorption by developing a microemulsion (ME) formulation (ME-DX).
View Article and Find Full Text PDFCharacteristics of Child Sexual Abuse Material in Peer-to-Peer Networks and Predictors of its Severity: Insights From Filenames.
Child Maltreat
January 2025
Child Rescue Coalition, Boca Raton, FL, USA.
The Internet has empowered millions of perpetrators who create and consume (CSAM), the current term replacing In this study, we coded data from a random sample of 2980 filenames from files shared in peer-to-peer (P2P) networks from U.S. IP addresses in 2021.
View Article and Find Full Text PDFSingle-molecule microscopy reveals that importin α slides along DNA while transporting cargo molecules.
Biochem Biophys Res Commun
January 2025
Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Katahira 2-1-1, Aoba-ku, Sendai, 980-8577, Japan; Department of Chemistry, Graduate School of Science, Tohoku University, Katahira 2-1-1, Aoba-ku, Sendai, 980-8577, Japan; Faculty of Engineering and Graduate School of Engineering, Gifu University, Yanagido 1-1, Gifu, 501-1193, Japan. Electronic address:
Importin α is a crucial player in the nucleocytoplasmic transport of nuclear localization signal (NLS)-containing cargo proteins and is suggested to bind to DNA directly. We hypothesized that importin α, after binding to DNA, may move along DNA via sliding or hopping. We investigated the movement dynamics of importin αs fused to AcGFP along DNA using single-molecule fluorescence microscopy and single-tethered DNA arrays.
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