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Long-term myocardial effects of noninvasive ventilation in patients with obesity hypoventilation syndrome.
Respir Med
September 2024
Department of Respiratory Medicine and Tuberculosis, P.J. Safarik University, Faculty of Medicine, and L. Pasteur University Hospital, Kosice, Slovakia. Electronic address:
Article Synopsis
- The study investigates the long-term effects of BiPAP therapy on heart function in patients with obesity hypoventilation syndrome (OHS), as these effects are not well understood.
- Thirteen patients participated, and after 3 and 12 months of BiPAP treatment, significant improvements in heart metrics like stroke volume and ejection time were observed, alongside reduced levels of inflammatory markers.
- Overall, the results indicate that BiPAP therapy can enhance cardiac function and decrease inflammation in patients with chronic OHS over a year of treatment.
Non-invasive monitoring of cardiac contractility: Trans-radial electrical bioimpedance velocimetry (TREV).
Psychophysiology
January 2024
Department of Psychological and Brain Sciences, University of California, Santa Barbara, California, USA.
We describe methods and software resources for a bioimpedance measurement technique, 'trans-radial electrical bioimpedance velocimetry' (TREV) that allows for the non-invasive monitoring of relative cardiac contractility and stroke volume. After reviewing the relationship between the measurement and cardiac contractility, we describe the general recording methodology, which requires impedance measurements of the forearm. We provide open-source Jupyter-based software (operable on most computers) for deriving cardiac contractility from the impedance measurements.
View Article and Find Full Text PDFCirculating Gal-3 and sST2 are associated with acute exercise-induced sustained endothelial activation: Possible relevance for fibrosis development?
Exp Physiol
October 2023
Exercise Physiology Lab, Institute of Human Movement Sciences and Sport, ETH Zurich, Zurich, Switzerland.
Long-term, intense endurance exercise training can occasionally induce endothelial micro-damage and cardiac fibrosis. The underlying mechanisms are incompletely understood. Twenty healthy, well-trained male participants (10 runners and 10 cyclists) performed a strenuous high-intensity interval training (HIIT) session matched by age, height, weight and maximal oxygen consumption.
View Article and Find Full Text PDFRelationship between Passive and Active Pulsations of Rat Artery as Vascular Extension of Frank-Starling Law.
Bull Exp Biol Med
April 2021
Department of Physiology, Research Institute of Experimental Cardiology, National Medical Research Center of Cardiology, Ministry of Health of the Russian Federation, Moscow, Russia.
The experiments on narcotized male rats (n=30) determined the parameters of passive and active pulsatile modes of isolated segment of femoral artery in situ. Rheographic elasticity (RE) and reactivity (RR) were correspondingly determined as the ratios of peak-to-peak (p2p) magnitudes of passive and active pulsatile oscillations of arterial electroimpedance (AEI) to p2p magnitude of BP undulations. The medians and interquartile ranges of RE and RR were 6 (3; 11) and 70 (40; 110) mΩ/mm Hg, respectively.
View Article and Find Full Text PDFIPG-based field potential measurement of cultured cardiomyocytes for optogenetic applications.
Biosens Bioelectron
May 2021
Institute of Biomedical Engineering, College of Electrical and Computer Engineering, National Chiao Tung University, 30010, Hsinchu, Taiwan. Electronic address:
Background: Electrophysiological sensing of cardiomyocytes (CMs) in optogenetic preparations applies various techniques, such as patch-clamp, microelectrode array, and optical mapping. However, challenges remain in decreasing the cost, system dimensions, and operating skills required for these technologies.
Objective: This study developed a low-cost, portable impedance plethysmography (IPG)-based electrophysiological measurement of cultured CMs for optogenetic applications.
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