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Nanosensor for Fe(II) and Fe(III) Allowing Spatiotemporal Sensing .
Nano Lett
January 2025
Disruptive & Sustainable Technologies for Agricultural Precision IRG, Singapore-MIT Alliance of Research and Technology, 1 CREATE Way, #03-06, Singapore 138602, Singapore.
Fluorescent nanosensors operating have shown recent success toward informing basic plant biology and agricultural applications. We developed near-infrared (NIR) fluorescent nanosensors using the Corona Phase Molecular Recognition (CoPhMoRe) technique that distinguish Fe(II) and Fe(III) species with limit of detection as low as 10 nM. An anionic poly(p-phenyleneethynylene) (PPE) polyelectrolyte wrapped single-walled carbon nanotube (SWNT) shows up to 200% turn-on and 85% turn-off responses to Fe(II) and Fe(III), respectively, allowing spatial and temporal analysis of iron uptake in both foliar and root-to-shoot pathways.
View Article and Find Full Text PDFUnderstanding hepcidin for iron management in pregnancy.
Transfus Med
January 2025
SUWON (Surgery, Oncology and Womens), Department of Haematology, University of Oxford, Oxford, UK.
Iron deficiency anaemia (IDA) poses a significant health challenge during pregnancy, affecting up to 30% of pregnant women in the UK. It has been linked to poor health outcomes for the mother, foetus, and the infant. Despite its prevalence and impact, current diagnostic and therapeutic approaches are limited.
View Article and Find Full Text PDFOverweight yet Undernourished: A Common Juxtaposition in the Specialist Diabetes Foot Service.
Int J Low Extrem Wounds
January 2025
Department of Endocrinology and Diabetes, St Vincent's Hospital, Sydney, New South Wales 2010, Australia.
Aims: To describe the nutritional status of people with diabetes-related foot complications and explore the association between nutrition and ulceration healing.
Methods: This retrospective cohort study included attendees of a diabetes foot service who completed a dietary questionnaire. Diet was compared to guideline recommendations and biochemical measures were recorded.
Integrative analysis of ferroptosis in the hypoxic microenvironment of gastric cancer unveils the immune landscape and personalized therapeutic strategies.
Front Oncol
January 2025
Department of Radiation Oncology, Qingdao People's Hospital Group (Jiaozhou), Jiaozhou Central Hospital of Qingdao, Qingdao, China.
Background: Ferroptosis is a cell death mode caused by excessive accumulation of lipid peroxides caused by disturbance of intracellular metabolic pathway, which is closely related to iron and cholesterol metabolism homeostasis. Its regulation within the hypoxic metabolic tumor microenvironment (TME) has the potential to improve the effectiveness of tumor immunotherapy. The predictive role of ferroptosis in gastric cancer (GC) hypoxia TME, particularly in relation to TME immune cell infiltration, has not been fully explained.
View Article and Find Full Text PDFRunning Low: A Seasonal Analysis of Micronutrient Deficiencies on External-Load Measures in Elite Female Rugby League Players.
Int J Sports Physiol Perform
January 2025
Research Institute for Sport and Exercise (UCRISE), University of Canberra, Canberra, ACT, Australia.
Unlabelled: Iron and vitamin D are essential for physiological mechanisms underpinning physical capacities characterizing team-sport performance. Yet, the impact of iron deficiency on physical capacities beyond endurance is not clear.
Purpose: The purpose of this study was to assess variations in seasonal micronutrient concentrations and how iron deficiency impacts external-load measures in elite female rugby league players.
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