Reactivity of lymphocytes from P. hamadryas monkeys carrying malignant lymphomas, directed against soluble antigens from allogeneic lymphomas, was investigated, using macrophage electrophoretic mobility (MEM) test. Twenty-three monkeys have been examined. Fourteen of them carried malignant lymphoma, including those with initial manifestations of malignant lymphoma, animals with a generalized process and those in the period of spontaneous remission, and 9 control animals (8 healthy baboons and one animal wih hepatoma). The macrophage electrophoretic mobility reduction higher than 10% was considered as positive. A positive reaction was observed in 78% of monkeys with malignant lymphoma. The positive MEM-test was noted already in the initial stage of the disease, and it remained positive in the period of spontaneous remission.
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