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Rectal Lymphogranuloma Venereum Mass Mimicking Colorectal Cancer.
Cureus
February 2025
Medical School, Florida International University, Herbert Wertheim College of Medicine, Miami, USA.
Chlamydia trachomatis-lymphogranuloma venereum (LGV) is a sexually transmitted infection (STI) and an uncommon cause of proctitis and rectal mass. When the rectum is affected, patients may experience symptoms such as rectal bleeding, pain, and tenesmus, which can resemble proctitis or proctocolitis and may be mistaken for malignancy. We present the case of a 40-year-old male patient with well-controlled HIV, who initially exhibited symptoms and imaging findings concerning for rectal neoplasia.
View Article and Find Full Text PDFThe Fate of the Rectum in Inflammatory Bowel Disease.
Surg Clin North Am
April 2025
Department of Surgery, University of Michigan Health System, 1500 East Medical Center Drive, TC 2101, Ann Arbor, MI 48109, USA; Division of Colorectal Surgery, University of Michigan Health System, Ann Arbor, MI 48109, USA. Electronic address:
For many patients with inflammatory bowel disease (IBD) proctocolitis, proctectomy offers symptom and disease control, albeit at the expense of a potentially morbid proctectomy. There are select situations, however, where definitively leaving an IBD rectum in situ, either in or out of intestinal continuity, may be a suitable alternative to proctectomy. This review explores the rare occasions where leaving the rectum in situ may be advisable and discusses the subsequent implications.
View Article and Find Full Text PDFOperative Management of Small and Large Bowel Crohn's Disease.
Surg Clin North Am
April 2025
Department of Colon & Rectal Surgery, Cleveland Clinic, 9500 Euclid Avenue, A30, Cleveland, OH 44195, USA. Electronic address:
The majority of patients with Crohn's disease, despite an ever-increasing number of advanced therapies, require abdominal surgery during their lifetime. In this review article, the authors provide a comprehensive overview of abdominal surgery for Crohn's disease, with an evidence-based focus on surgery for upper gastrointestinal Crohn's disease, bowel-preserving surgery with strictureplasties, selection of ileocolic anastomotic technique for terminal ileal Crohn's disease, extended resections and proctectomy for Crohn's proctocolitis, intentional ileoanal pouch for Crohn's disease, and several "hot topics" including early surgery for ileocolic Crohn's disease, and surgical approaches that target the mesentery including the Kono-S anastomosis and extended mesenteric excision.
View Article and Find Full Text PDFFactors influencing the natural history of non-IgE-mediated gastrointestinal food allergies in paediatric age: a prospective multicentre cohort study.
BMJ Paediatr Open
February 2025
Department of Translational Medical Science, University of Naples Federico II, Napoli, Campania, Italy
Background: We aimed at identifying the factors influencing the natural history of non-IgE-mediated gastrointestinal food allergies (non-IgE-GIFA), a group of common paediatric conditions including food protein-induced: enteropathy (FPE), allergic proctocolitis (FPIAP), enterocolitis syndrome (FPIES), and motility disorders (FPIMD).
Methods: Prospective multicentre cohort study involving paediatric patients (both sexes, aged ≤14 y) with non-IgE-GIFA diagnosed and followed for 24 months at a Tertiary Centre for Paediatric Allergy, Gastroenterology and Nutrition. Anamnestic and clinical data were collected from all enrolled patients.
Food Protein-Induced Allergic Proctocolitis: Real-World Experience from an Italian Cohort.
Nutrients
December 2024
Allergy Unit, Meyer Children's Hospital IRCCS, 50139 Florence, Italy.
: Food protein-induced allergic proctocolitis (FPIAP) is a non-IgE-mediated food allergy, usually presenting as bloody stools in breastfed, well-appearing, and regularly growing infants. The aim of our study was to describe the clinical features of Italian infants affected by FPIAP and their management and natural history in a real-life setting. : A retrospective, observational study was performed at two tertiary pediatric hospitals (Florence and Trieste), including FPIAP-diagnosed infants between 2012 and 2022.
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