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A rare cause of chronic cough and hemoptysis: Broncholithiasis.

Indian J Thorac Cardiovasc Surg

February 2025

Department of Radiology, Medical Faculty, Ataturk University, Erzurum, Turkey.

The term "broncholithiasis" is defined as the presence of calcified material in the tracheobronchial tree. Broncholithiasis is usually asymptomatic when it does not cause any erosion in the airways. However, the most common symptoms of broncholithiasis include cough, hemoptysis, and wheezing due to irritation of the airways and surrounding tissues.

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Article Synopsis
  • Acquired benign tracheoesophageal and bronchoesophageal fistulas (TEFs) are often linked to granulomatous infections, primarily caused by medical interventions, with rare organisms like Candida albicans and Actinomyces involved.
  • A case study describes a patient experiencing symptoms like cough and weight loss, leading to the discovery of a fistula and complications such as actinomycetoma and broncholithiasis due to the dual infection.
  • The report emphasizes the importance of recognizing this uncommon co-infection and provides a diagnostic algorithm to aid healthcare professionals in identifying and treating TEs effectively.
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Case Series Summary: Cystic bronchiectasis was diagnosed in three cats with known histories of chronic coughing using CT and histopathology. CT of the lungs revealed large space-occupying lesions that compressed and displaced unaffected pulmonary parenchyma and vessels. The masses were soft tissue attenuating in two cases and gas-cavitated with areas of dependent fluid in one case.

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Broncholithiasis due to pulmonary histoplasmosis causing central airway obstruction and broncho-mediastinal fistula is a rare complication in the pediatric population. A 16-year-old previously healthy female was referred to a university hospital for worsening cough and shortness of breath for over a two-year period. Radiologic investigation revealed a calcified subcarinal lymph node eroding into the left mainstem bronchus causing central airway obstruction and collapse of the left lower lobe.

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Asymptomatic Broncholithiasis and Infection: A Case Report and Literature Review.

Infect Drug Resist

May 2023

Department of Respiratory and Critical Care Medicine, The Fourth Affiliated Hospital, International Institutes of Medicine, Zhejiang University School of Medicine, Yiwu, 322000, People's Republic of China.

Broncholithiasis coupled with infection is a rare disease of the respiratory system with complex pathogenesis and non-specific clinical manifestations that can be easily confused with other types of infectious diseases of the respiratory system. The lack of pertinent clinical manifestations in patients increases the risk of clinical misdiagnosis, omission, and incorrect treatment plan selection, which can result in permanent lung structural alterations and lung function decompensation and ultimately harm the lung. We report a rare case of asymptomatic broncholithiasis coupled with infection that was treated at our hospital and discuss the pathophysiology, diagnosis, differential diagnosis, and prognostic follow-up course.

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