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Background: Primary dysmenorrhea (PD) is characterized by discomfort with no organic etiology (no pelvic disease), recurring pain, or lower abdominal cramps that start between the first 8-72 h of menstruation. Cupping therapy uses a tool to form a vacuum at certain points on the skin.

Objectives: We investigated the mechanism of pain relief caused by cupping therapy in primary dysmenorrhea that is played by cupping therapy in PD.

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Perioperative complications of middle cerebral artery occlusion in rats alleviated by human umbilical cord mesenchymal stem cells.

Naunyn Schmiedebergs Arch Pharmacol

December 2024

Regenerative Medicine Research Center of The First People's Hospital of Yunnan Province, Affiliated Hospital of Kunming University of Science and Technology, Xishan District, 157 Jinbi Road, Kunming, 650000, Yunnan, China.

Article Synopsis
  • Acute ischemic stroke treatments often face challenges like high complication rates, which negatively impact patient recovery and survival.
  • Human umbilical cord mesenchymal stem cells (hucMSCs) show promise as a potential cell therapy due to their ability to differentiate and regulate immune responses.
  • In a study conducted on rats, hucMSCs treatment improved neurological function, reduced brain tissue ischemia, enhanced postoperative survival, and lessened complications related to stress and anesthesia recovery following a stroke model.
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Background: The aim of this study was to examine variations in stress, metabolic, and physiological parameters of horses used in the traditional equestrian team sport of Kök-Börü in relation to winning and losing outcomes.

Material And Methods: To accomplish this, blood samples were taken from horses on four different teams who participated in two separate games, both before and after game. These samples were used to measure levels of cortisol, ACTH, beta-endorphin, adrenaline, noradrenaline, triiodothyronine (T3), and thyroxine (T4) via species-specific commercial ELISA kits.

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Article Synopsis
  • This study explored how the endocannabinoid system (EC) and endogenous opioids, specifically beta-endorphin (BE), interact in managing pain and opioid use after cesarean delivery in pregnant patients.
  • Findings showed that higher levels of specific endocannabinoids in the blood and cerebrospinal fluid were associated with reduced use of opioid painkillers, particularly in patients with low BE levels.
  • Understanding these interactions could lead to better pain management strategies in various clinical settings.
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Objectives: To observe the clinical effect of wrist-ankle acupuncture on postpartum abdominal pain and its influence on serum beta-endorphin (β-EP) level in puerpera.

Methods: Seventy patients with postpartum abdominal pain were randomly divided into an acupuncture + herbal medication group (35 cases, 1 case dropped out) and a herbal medication group (35 cases, 2 cases dropped out). In the herbal medication group, 1 day after delivery, modified decoction was taken orally, one dose a day.

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