It was demonstrated spectrophotometrically that in the hemoglobin-free perfused rat heart met- and ferrylmyoglobins formed upon infusion of sodium nitrite, and ethyl hydroperoxide were reduced to form oxymyoglobin with a half time of about 3 and 4 min, respectively. The rate of metmyoglobin reduction was about 30 nmol/min/g wet weight in the rat heart.
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