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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1715138 | PMC |
| http://dx.doi.org/10.1136/bmj.281.6255.1641-c | DOI Listing |
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First-in-Human Helical-Fixation Leadless Pacemaker in the Left Atrium for D-Transposition With Atrial Switch Procedure.
JACC Case Rep
January 2025
Division of Cardiology, Electrophysiology Section, Adult Congenital Arrhythmia Clinic, Emory University, Atlanta, Georgia, USA.
Background: The atrial switch procedure is accompanied by a very high rate of sinus node dysfunction. Baffle stenosis is a common problem with transvenous pacemaker leads in this scenario.
Case Summary: We present a first-in-human case of a leadless pacer (LP) in the left atrium in a patient with prior atrial switch for transposition and sinus node dysfunction complicated by multiple abandoned leads, superior baffle occlusion, and failed extraction.
Clonal Hematopoiesis Is Associated With Adverse Clinical Outcomes and Left Ventricular Remodeling in Aortic Stenosis.
JACC Adv
February 2025
Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Background: Clonal hematopoiesis of indeterminate potential (CHIP) has been linked to intensified systemic inflammation and represents a novel risk factor for atherosclerotic cardiovascular diseases, including aortic stenosis (AS).
Objectives: This study aimed to assess the clinical impact of CHIP in a cohort of severe AS patients undergoing transcatheter aortic valve implantation (TAVI).
Methods: We enrolled 110 severe AS patients in this retrospective study.
Objective: Fluoropyrimidine chemotherapy is a first-line treatment for many gastrointestinal (GI) cancers, however, cardiotoxicity concerns may limit administration in patients with pre-existing cardiovascular disease (CVD). This study investigated the association of pre-existing CVD with use of fluoropyrimidine chemotherapy in tumour-eligible GI cancer patients.
Methods And Analysis: National cancer registry data from the Virtual Cardio-Oncology Research Initiative from England between 2014 and 2018 was used to identify GI cancer patients eligible to receive fluoropyrimidine chemotherapy.
Trauma patients with metastatic cancer undergoing emergent surgery: A matched cohort analysis.
Surg Open Sci
August 2024
University of California, Irvine, Department of Surgery, Division of Trauma, Burns and Surgical Critical Care, Orange, CA, USA.
Background: There is a paucity of literature guiding trauma surgeons in the care of patients with active metastatic cancer (MC). Even less is known regarding outcomes for MC patients requiring emergent surgery after trauma. We hypothesized that trauma patients with active Metastatic Cancer (MC) have an increased mortality rate and undergo increased rates of withdrawal of care (WoC) within 72-hours following emergent operations, compared to similarly matched patients without MC.
View Article and Find Full Text PDFCorrelation of diabetes and adverse outcomes in hospitalized COVID-19 patients admitted to a tertiary hospital in China during a small-scale COVID-19 outbreak.
PeerJ
January 2025
Department of Endocrinology, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Background: The aim of this study was to investigate the impact of diabetes on mortality and adverse outcomes in COVID-19 patients and to analyse the associated risk factors.
Methods: This is a retrospective cohort study in 500 hospitalized patients with COVID-19 infection (214 with diabetes and 286 without diabetes) admitted to a tertiary hospital in China from December 2022 to February 2023. Demographic information, clinical characteristics and outcomes were collected.
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