Brief clinical characteristics and microscopic structure of a peculiar focal granulomatosis, macrophagal affection of the urinary bladder mucous membrane, are described. Microscopically, malacoplakia of the urinary bladder has a zonal structure the presence of which is important for differential diagnosis from some tumours, particularly myoma consisting of myoblasts and malignant histiocytoma. The presence of small rounded basophilic inclusions (Mikhaelis--Gutmann bodies) is a characteristic feature of malacoplakia.
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