Fibres from tail tendons of male rats aged 1--18 months were stretched to breaking point by an 'Instron' tensile apparatus. The energy absorbed during stretching of the tendon was calculated. A sharp increase was found in the energy value during the first 6 months of postnatal life. The following components of this energy were also evaluated: (1) energy absorbed during the period of linear relationship between force and extension; (2) energy absorbed during the period of non-linear relationship. Both components showed rapid increases in value during the first 6 months after birth, after which they levelled off.
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BMC Chem
January 2025
Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh, 11451, Saudi Arabia.
For paediatric patients suffering from neurofibromatosis, Selumetinib (SEL) is the only approved drug. Here an original ecofriendly and high pace method is introduced using 96- microwell spectrophotometric assay (MW-SPA) to measure SEL content in bulk and commercial pharmaceutical formulation (Koselugo capsules). This assay was relied on in-microwell formation of a coloured charge transfer complex (CTC) upon interaction of SEL with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ).
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January 2025
Department of Biophysics, School of Basic Medical Sciences, Health Science Centre, Xi'an Jiaotong University, Xi'an, Shaanxi, P. R., China.
The rise of antibiotic-resistant Gram-positive bacterial infections poses a significant threat to public health, necessitating the exploration of alternative therapeutic strategies. A photosensitizer (PS) can convert energy from absorbed photon into reactive oxygen species (ROS) for damaging bacteria. This photoinactivation action bypassing conventional antibiotic mechanism is less prone to resistance development, making antibacterial photodynamic therapy (aPDT) highly efficient in combating Gram-positive bacteria.
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January 2025
Jilin University, State Key Laboratory of Supramolecular Structure and Materials, 2699 Qianjin Street, 130012, Changchun, CHINA.
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January 2025
Department of Physics and Astronomy & Wright Center for Photovoltaic Innovation and Commercialization, The University of Toledo, Toledo, Ohio 43606, United States.
Wide band gap FACsPb(IBr) perovskite photovoltaic (PV) devices are measured by spectroscopic ellipsometry in the through-the-glass configuration and analyzed to determine the complex optical property spectra of the perovskite absorber as well as the structural properties of all constituent layers. This information is used to simulate external quantum efficiency (EQE) spectra, to calculate PV device performance parameters such as short circuit current density, open circuit voltage, fill factor, and power conversion efficiency, and to develop strategies for increasing the accuracy of predictions. Simulations and calculations tend to overestimate PV device performance parameters, undermining the accuracy and usefulness of those simulations.
View Article and Find Full Text PDFJDS Commun
January 2025
Department of Animal Science, Universidade Federal de Lavras, Lavras, MG, Brazil, 37200-900.
The National Academies of Sciences, Engineering, and Medicine (NASEM, 2021) milk protein yield (MPY) prediction equation includes independent and additive effects of digestible energy intake and absorbed EAA. Our objective was to evaluate the NASEM MPY prediction and EAA use efficiency in Holstein cows in pens from commercial farms. Data collected from 12 Brazilian herds were used.
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