Many arboviruses can cause febrile illness in man, with or without rash, quite apart from yellow fever and the aetiological agents of haemorrhagic fevers. Exanthema are one of the commonest signs. Neuro-vascular attacks frequently occur and in some cases meningitic complications can happen. Diagnosis is often difficult: viraemia is of short duration and complement fixing antibodies do not appear consistently in convalescent serum. In Central and West Africa, 19 different arboviruses have been implicated either by isolation or by serological conversion. Some were isolated from man for the first time.

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