A rare case of giant cell tumour of first metacarpal bone which was aggressive in its clinical behaviour but histologically benign, is reported in a thirty-one year old male. The tumour was excised en-bloc with disarticulation of the thumb and index finger with a gratifying result. The literature on giant-cell-tumour of the metacarpal bone is reviewed.
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http://dx.doi.org/10.1016/s0072-968x(80)80055-6 | DOI Listing |
J Biomech Eng
January 2025
Human-Centric Design Research Lab, Department of Mechanical Engineering, Texas Tech University, Lubbock, TX 79409, USA.
This study presents a comprehensive finite element model for the human wrist, constructed from a CT scan of a 68-year-old male (type I wrist). This model intricately captures the bone and soft tissue geometries to study the biomechanics of wrist axial loading through tendon-driven simulations and grasping biomechanics using metacarpal loads. Validation is carried out by assessing the radial and ulnar axial loading distribution, radiocarpal articulation contact patterns, and other standard finite element metrics.
View Article and Find Full Text PDFActa Orthop
January 2025
Department of Orthopaedic Surgery, Danderyd Hospital, Stockholm; 2 Department of Clinical Sciences at Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden.
Background And Purpose: Hand fractures are commonly presented in emergency departments, yet diagnostic errors persist, leading to potential complications. The use of artificial intelligence (AI) in fracture detection has shown promise, but research focusing on hand metacarpal and phalangeal fractures remains limited. We aimed to train and evaluate a convolutional neural network (CNN) model to diagnose metacarpal and phalangeal fractures using plain radiographs according to the AO/OTA classification system and custom classifiers.
View Article and Find Full Text PDFJ Clin Med
December 2024
Department of Hematology and Immunology, Kanazawa Medical University, 1-1 Daigaku, Uchinada, Kahoku-gun 920-0293, Japan.
: Osteoporosis is common in rheumatoid arthritis (RA), occurring either systemically or locally around inflamed joints. Decreased metacarpal bone density is a known marker of RA progression and hand function impairment. Although RA is generally characterized by symmetrical arthritis, some patients exhibit asymmetrical joint involvement.
View Article and Find Full Text PDFJ Clin Med
December 2024
Department of Plastic and Hand Surgery, University Hospital of Basel, 4031 Basel, Switzerland.
: Most metacarpal fractures are isolated, simple, closed, and stable fractures and located distally. They are often caused by accidental falls, strikes by humans, by objects or traffic accidents. The majority can be treated conservatively.
View Article and Find Full Text PDFbioRxiv
December 2024
Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA, USA.
Bones develop to structurally balance strength and mobility. Bone developmental dynamics are influenced by whether an animal is ambulatory at birth (, precocial). Precocial species, such as goats, develop advanced skeletal maturity in utero, making them useful models for studying the dynamics of bone formation under mechanical load.
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