In the Womens Hospital Peine from July 1, 1976 to December 31, 1979 503 artificial abortions were carried out by intracervical application of 3 mg PGF2-Alpha-Gel. In 82.5% of the cases patients had a spontaneous abortion or a cervical dilatation. Gastrointestinal side-effects were observed in 10.5% of the cases. 27.6% of the patients complained of acute pain. Complications due to the following mechanical dilatation did not occur. In three cases patients went into a state of shock after the gel-application. This, however, was quickly reversible. A systemic reaction an occur when PGF2-Gel is applied locally.
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http://dx.doi.org/10.1055/s-2008-1037237 | DOI Listing |
Arch Gynecol Obstet
June 2024
Department of Obstetrics and Gynaecology, College of Medicine and Sagar Dutta Hospital, 578, Barrackpore Trunk Road, Kolkata, West Bengal, 700058, India.
Purpose: To evaluate the efficacy and safety of transdermal glycerol trinitrate skin patches as an additive and effective agent for facilitating cervical ripening for labour induction.
Methods: This was a double-blinded prospective randomised clinical trial carried out in a major obstetric unit in India. Women who planned for labour induction were randomly allocated for induction either by combined application of glycerol trinitrate skin patches [GTN patch] and intracervical dinoprostone gel or by the gel only.
Objective: Comparison of systems to detect sentinel lymph node in endometrial carcinoma using indocyanine green. Robotic Firefly Da Vinci fluorescence imaging system (Intuitive Surgical Inc., Sunnyvale, CA, USA) vs.
View Article and Find Full Text PDFCancers (Basel)
May 2022
Department of Gynecology and Obstetrics, Ruhr-Universität Bochum, Marien Hospital Herne, 44625 Herne, Germany.
Cervical dysplasia is a common precancerous lesion affecting 1% to 2% of women worldwide. Significant progress in the diagnosis and treatment of cervical dysplasia have been made in the last decade. We performed a systematic literature search of the databases PubMed and Cochrane Central Register of Controlled Trials to identify controlled clinical trials reporting on the efficacy and safety of diagnostic and therapeutic interventions for cervical dysplasia.
View Article and Find Full Text PDFEur J Obstet Gynecol Reprod Biol
March 2022
Department of Gynecology and Obstetrics, University Hospital Merkur, Zajčeva 19, 10000 Zagreb, Croatia; Department of Gynecology and Obstetrics, School of Medicine, University of Zagreb, Šalata 2, 10000 Zagreb, Croatia. Electronic address:
Objective: The aim of this study was to compare intracervical (IC) and intravaginal (IV) application of prostaglandin E2 (PGE2) for labor induction in term pregnancies with unfavorable cervix.
Study Design: This prospective randomized trial included 212 pregnant women with term pregnancy and unfavorable cervix randomly assigned for labor induction with either IC (0.5 mg) or IV (2 mg) PGE2 formulation.
J Obstet Gynaecol
February 2022
Fertility Consultant, Apollo Fertility, Chennai, India.
The purpose of this study was to assess the effect of vaginal pH on efficacy of intracervical dinoprostone gel (PGE2) for labour induction, progression and induction delivery interval. A cross-sectional study was done among 150 term pregnant women planned for induction with unfavourable Bishop's score ≤5. Women were categorised into two groups based on vaginal pH >4.
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