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Nanodrugs Targeting Key Factors of Ferroptosis Regulation for Enhanced Treatment of Osteoarthritis.
Adv Sci (Weinh)
January 2025
Institute of Orthopaedics and Traumatology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Department of Orthopedic Surgery, Hangzhou Hospital of Traditional Chinese Medicine, Zhejiang Chinese Medical University, Hangzhou, 310000, China.
Osteoarthritis (OA) is a globally prevalent degenerative joint disease. Recent studies highlight the role of ferroptosis in OA progression. Targeting ferroptosis regulation presents a promising therapeutic strategy for OA; however, current research primarily focuses on single targets associated with ferroptosis.
View Article and Find Full Text PDFApplying microbial biostimulants and drought-tolerant genotypes to enhance barley growth and yield under drought stress.
Front Plant Sci
January 2025
Microbial Biotechnology and Bioactive Molecules Laboratory, Sciences and Technology Faculty, Sidi Mohamed Ben Abdellah University, Fez, Morocco.
With climate change, the frequency of regions experiencing water scarcity is increasing annually, posing a significant challenge to crop yield. Barley, a staple crop consumed and cultivated globally, is particularly susceptible to the detrimental effects of drought stress, leading to reduced yield production. Water scarcity adversely affects multiple aspects of barley growth, including seed germination, biomass production, shoot and root characteristics, water and osmotic status, photosynthesis, and induces oxidative stress, resulting in considerable losses in grain yield and its components.
View Article and Find Full Text PDFAppropriateness and inappropriate medication predictors of stress ulcer prophylaxis in the intensive care unit.
Front Pharmacol
January 2025
Department of Pharmacy, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
Introduction: Preventive drugs for stress ulcers are widely and unreasonably used in the Intensive Care Unit (ICU). This study aims to examine the appropriate utilization of medications for stress ulcer prophylaxis (SUP) and identify factors that contribute to the inappropriate use of these medications in the ICU of the Second Hospital of Shanxi Medical University.
Methods: Patient cases admitted to the ICU during the period from May 2022 to May 2023 were extracted from the hospital's information management system.
The effect of a mindfulness-based cognitive therapy program on the spiritual health of mothers of infants admitted to the neonatal intensive care unit.
Front Psychol
January 2025
Nursing Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Introduction: The birth and admission of a premature infant to the NICU is often an unexpected experience and a mental and spiritual challenge for families. Spiritual health is an influential factor affecting how a mother faces and endures a stressful situation. Improving the mother's spiritual health requires cognitive therapy approaches, including mindfulness techniques.
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