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Enhancing the control of respiratory virus spread: a comprehensive approach integrating airborne virus detection, aerological investigations, and airflow modeling for practical implementation.
Infect Control Hosp Epidemiol
January 2025
Virology Department, AP-HP, Hôpital Saint-Louis, Paris, France.
Objective: Patients with chronic kidney disease suffer from immune dysfunction, increasing susceptibility to infections. The aim of the study was to investigate air contamination with respiratory viruses in a dialysis unit at a quaternary hospital using molecular detection techniques and to analyze airflow dynamics through computational fluid dynamics (CFD) simulations for a comprehensive assessment of air transmission risks.
Methods: We conducted dialysis unit air sampling using AerosolSense™ samplers.
Results from a UK consensus about the optimal prescribing of medium strength triple therapy in uncontrolled adult asthma patients in the NHS.
J Family Med Prim Care
December 2024
Medicines Evaluation Unit, Manchester University National Health Service Foundation Trust, University of Manchester, Manchester, United Kingdom.
Context: An inhaled corticosteroid (ICS) in combination with a long-acting β2-agonist (LABA) is a common treatment approach for asthma patients not controlled on ICS alone, but a significant proportion of patients remain uncontrolled on this combination and treatment adherence can also be a challenge. One of the options for adults whose asthma is uncontrolled in an ICS/LABA is the addition of a long-acting muscarinic receptor antagonist (LAMA), an approach commonly referred to as 'triple therapy'. The use of medium-strength ICS/LABA/LAMA is established in treating chronic obstructive pulmonary disease but is less well-established in asthma.
View Article and Find Full Text PDFDiscitis: A Rare Presentation and Review of Literature.
HCA Healthc J Med
December 2024
University of Florida College of Medicine, Gainesville, FL.
Background: is an anaerobic gram-negative coccus found as a commensal organism in the oral, respiratory, gastrointestinal, and genitourinary tract of humans. Rarely, it can cause serious infections by the production of lipopolysaccharide, an endotoxin. Although most infections occur in immunocompromised individuals, we herein describe cases of discitis, a rare presentation of , in immunocompetent patients.
View Article and Find Full Text PDFImproved Pulmonary Hypertension and Heart Failure by Diaphragmatic Plication and Tracheal Resection.
Ann Thorac Surg Short Rep
December 2024
Department of Thoracic Surgery, The University of Tokyo Hospital, Tokyo, Japan.
The patient was a 66-year-old man who developed exacerbation of respiratory and heart failure that necessitated tracheal intubation. The exacerbation was considered to be largely caused by asthma-chronic obstructive pulmonary disease overlap syndrome and type 3 pulmonary hypertension. However, left diaphragmatic eventration and tracheal stenosis were also found.
View Article and Find Full Text PDFAdult Plastic Bronchitis: A Rare Cause for Chronic Productive Cough.
Ann Thorac Surg Short Rep
September 2024
Division of Thoracic and Cardiovascular Surgery, Lahey Hospital and Medical Center, Burlington, Massachusetts.
Plastic bronchitis is a rare disease with serious morbidity. We report a case of a 48-year-old male smoker with a past medical history of diabetes, emphysema, recurrent respiratory infections, a worsening productive cough, and increased oxygen requirement over the past 3 months. Often described in the pediatric population, it is important to maintain plastic bronchitis in the differential when considering unresolving pulmonary conditions with chronic sputum production.
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