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Aim of the study was investigation of association of polymorphic markers Gly389Arg and Ser49Gly of ADRB1 gene, Gly1l6Arg and Glu27Gln of ADRB2 gene, Trp64Arg of ADRB3 gene, and 825 of GNB3 gene with structural and functional peculiarities of the left ventricular (LV) myocardium in patients with hypertensive disease. We examined 177 patients - 83 (46.9%) men and 94 (53.
View Article and Find Full Text PDFStress generally demonstrates the maximum stress of an organism at a specific moment, which is frequently important in evaluating the body's condition. The stress is generally accepted to be determined by the activity of adrenaline and the higher excitation of alpha- than beta-adrenoceptors. The present investigation has been undertaken to specify the relation of the above-mentioned structures with humoral immunological parameters.
View Article and Find Full Text PDFA study on the testing unit was made of a contractile function of ureteral fragments removed at reconstructive operations for vesicoureteral reflux (VUR), neuromuscular dysplasia (NMD) and pelvoureteral segment stricture (PUSS). The study parameters (wall rigidity, amplitude of the contractions, potassium depolarization contracture, responses to adrenoreactive drugs) in patients with VUR were close to normal, whereas in those with NMD or PUSS changed significantly, especially in PUSS patients. Ureteral contractility impairment was heterogenic in all the groups, varying from intact to lost and did not correlate either with age or the disease stage.
View Article and Find Full Text PDF[New approaches to the system regulating the aggregate state of the blood].
Fiziol Zh (1978)
May 1992
It is shown that in the organism there is an adrenoreactive system of the aggregate blood state regulation (ABSR) including alpha- and beta-adrenoreactive structures of hypothalamus, amygdalar complex and peripheral vessels. The ABSR system consists of two subsystems, each possessing specific action. Both subsystems interact in the reciprocal manner by the mechanism of feedbacks and can exert a modulating effect on each other.
View Article and Find Full Text PDFThe pregnant suffering from nephropathies were found to have autonomic nervous control disorders closely related to the major platelet vascular and plasma hemostatic, hemodynamic, and microcirculatory parameters. A combined examination of the macro- and ++micro-hemodynamics and status of adrenoreactive structures assessed the adaptation of a pregnant to nephropathy and her reserve potentialities. Adrenoreactive structure derangement is a measure of the severity of nephropathy.
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