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Effect of gut microbiota changes on cytokines IL-10 and IL-17 levels in liver transplantation patients.
BMC Infect Dis
January 2025
Botany and Microbiology Department, Faculty of Science, Menoufia University, Shebeen El-Kom, Egypt.
Background: Liver transplantation (LT) is a critical intervention for individuals with end-stage liver disease; yet, post-transplant problems, especially infections, graft rejection, and chronic liver disease, are often linked to systemic inflammation. Cytokines, small signaling molecules, significantly influence immune responses during and post-liver transplantation. Nonetheless, the intricate relationships among cytokines, immune responses, and the gut microbiota, especially gut dysbiosis, are still inadequately comprehended.
View Article and Find Full Text PDFA single-cell RNA sequencing dataset of peripheral blood cells in long COVID patients on herbal therapy.
Sci Data
January 2025
Department of Biochemistry & Molecular Biology, Ajou University School of Medicine, Suwon, 16499, South Korea.
Following the coronavirus disease 2019 (COVID-19) pandemic, the rise of long COVID, characterized by persistent respiratory and cognitive dysfunctions, has become a significant health concern. This leads to an increased role of complementary and alternative medicine in addressing this condition. However, our comprehension of the effectiveness and safety of herbal medicines for long COVID remains limited.
View Article and Find Full Text PDFIndications for and limitations of laparoscopic anatomical liver resection: assessment of postoperative complications stratified by complexity of liver resection.
Surg Endosc
January 2025
Department of Hepato-Biliary-Pancreatic Surgery, Osaka City General Hospital, 2-13-22 Miyakojima-Hondori, Miyakojima-Ku, Osaka, 534-0021, Japan.
Background: Although complex anatomical liver resections are more often being performed laparoscopically, the short-term outcomes following laparoscopic anatomical liver resection (LALR), its optimal indications, and limitations remain unclear. This study aimed to clarify the indications for and limitations of LALR by assessing the short-term outcomes.
Methods: This retrospective study included 233 patients who underwent LALR.
An insight into the molecular mechanisms of persistent organic pollutants (POPs) mediated dysregulation of glucose and lipid homeostasis in Heteropneustes fossilis.
Gen Comp Endocrinol
January 2025
Molecular Endocrinology and Toxicology Laboratory (METLab), Department of Zoology, Banaras Hindu University, Varanasi, India. Electronic address:
The study emphasises how ubiquitous persistent organic pollutants (POPs) are and how terrible they are for the environment, specifically because of their tendency to build up in living things and cause a variety of health problems, including diabetes, obesity, and cardiovascular disorders. Due to POPs affinity for lipid-rich tissues, they accumulate in a variety of organs, where they cause metabolic disruption and initiate various anabolic pathways. Studies that use fish as a model organism clarify the metabolic effects of POPs, demonstrating non-adipose lipid accumulation and abnormal glucose homeostasis.
View Article and Find Full Text PDF"Minimal-Advice" on Salt Intake: Results of a Multicentre Pilot Randomised Controlled Trial on Hypertensive Patients.
High Blood Press Cardiovasc Prev
January 2025
Department of Clinical Medicine and Surgery, ESH Excellence Center of Hypertension, "Federico II" University of Naples Medical School, Via S. Pansini, 5, 80131, Naples, Italy.
Introduction: A strong and well-known association exists between salt consumption, potassium intake, and cardiovascular diseases. MINISAL-SIIA results showed high salt and low potassium consumption in Italian hypertensive patients. In addition, a recent Italian survey showed that the degree of knowledge and behaviour about salt was directly interrelated, suggesting a key role of the educational approach.
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