Hypercalcaemic coma leads to changes in myocardial efficiency and skeletal muscle tone. It is difficult to recommend a favourable anaesthetic agent for such a rare but acute and serious clinical condition. Our experiences are against administration of enflurane. It seems to be that neurolept anaesthesia is the most suitable method for those patients.
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[Hypercalcaemia: intensive care or general ward].
Aktuelle Urol
February 2024
Urologie, Universitätsklinikum des Saarlandes und Medizinische Fakultät der Universität des Saarlandes, Homburg, Germany.
Hypercalcaemia is a life-threatening electrolyte imbalance, which not only occurs in the context of an endocrinological disease but is also frequently associated with a tumour. Its severity is determined by the level of deviation from normal, acuity of occurrence, and severity of the symptoms. These are unspecific, can affect any organ system and ultimately result in a life-threatening hypercalcaemic crisis characterised by cardiac arrhythmia, metabolic acidosis, exsiccosis, fever, psychotic states and, ultimately, coma.
View Article and Find Full Text PDFManagement of primary hyperparathyroidism in pregnancy: a case series.
Endocrinol Diabetes Metab Case Rep
May 2019
Department of Diabetes and Endocrinology, Cambridge University NHS Foundation Trust, Cambridge, UK.
Primary hyperparathyroidism (PHPT) is characterised by the overproduction of parathyroid hormone (PTH) due to parathyroid hyperplasia, adenoma or carcinoma and results in hypercalcaemia and a raised or inappropriately normal PTH. Symptoms of hypercalcaemia occur in 20% of patients and include fatigue, nausea, constipation, depression, renal impairment and cardiac arrythmias. In the most severe cases, uraemia, coma or cardiac arrest can result.
View Article and Find Full Text PDFHyperparathyroidism during Pregnancy- A Diagnostic and Therapeutic Challenge.
J Clin Diagn Res
September 2017
Director Professor and Head, Department of Obstetrics and Gynaecology, UCMS and GTB Hospital, Delhi, India.
Primary Hyperparathyroidism (PHP) is a rare event in pregnancy; Maternal complications in PHP patients can be as high as 67%. It can be overlooked easily because of many similar complaints shared by hyperparathyroidism and pregnancy such as nausea and vomiting, gastritis, bone aches, easy fatigability. Hypercalcemic crisis can develop resulting in coma and death.
View Article and Find Full Text PDF[Hypercalcemic crisis and hypocalcemic tetany].
Internist (Berl)
October 2017
Abteilung Innere Medizin I und Klinische Chemie, Sektion Osteologie, Medizinische Universitätsklinik Heidelberg, INF 410, 69120, Heidelberg, Deutschland.
A serum calcium level >3.5 mmol/l together with clinical symptoms such as muscle weakness, fatigue, nausea, vomiting, pancreatitis or even coma are characteristic for a hypercalcemic crisis (HC). Primary hyperparathyroidism (1HPT) and malignancy-associated hypercalcemia are the most frequent causal diseases for a HC.
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