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Modulation of Affective and Sensory Qualities of Acute Nociceptive Pain by Curcuma longa and Boswellia serrata Extract Formulation: A Randomized, Double-Blind, Placebo-Controlled Design in Subjects With Exercise-Induced Acute Musculoskeletal Pain.
Cureus
January 2025
Orthopedics, Nirmal Hospital, Jhansi, IND.
Introduction Excessive repetitive physical activity most often leads to acute musculoskeletal pain. The management of acute pain is one of the primary concerns. The nociceptive pain has both sensory and affective qualities, patterns, and intensity.
View Article and Find Full Text PDFRole of macrophage polarization in diabetic foot ulcer healing: A bibliometric study.
World J Diabetes
January 2025
Department of Surgery, Longkou Traditional Chinese Medicine Hospital, Yantai 265701, Shandong Province, China.
Background: Diabetic foot ulcers (DFUs) are a significant contributor to disability and mortality in diabetic patients. Macrophage polarization and functional regulation are promising areas of research and show therapeutic potential in the field of DFU healing. However, the complex mechanism, the difficulty in clinical translation, and the large heterogeneity present significant challenges.
View Article and Find Full Text PDFFacial Fat Grafting Cannula: A Tool to Facilitate Closed Irrigation in Flexor Tenosynovitis.
Plast Reconstr Surg Glob Open
January 2025
From the Division of Plastic and Reconstructive Surgery, Mayo Clinic, Rochester, MN.
Pyogenic flexor tenosynovitis (PFT), also known as septic or suppurative flexor tenosynovitis, is a closed-space infection of the hand's flexor tendon sheath that necessitates timely diagnosis and treatment. The treatment consists of antibiotic therapy often combined with prompt surgical treatment. The most common surgical approach is the closed irrigation technique, which involves inserting a 16-gauge angiocatheter in the proximal aspect of the flexor tendon sheath, leaving the distal end of the Brunner incision open during the irrigation process.
View Article and Find Full Text PDFNorthern Lights Neuroscience Symposium 2024: Expanding Spectrum of Common Dementia Disorders.
Free Neuropathol
January 2024
The Northern Lights Neuroscience Symposium 2024 "Expanding Spectrum of Common Dementia Disorders" was held in Hanasaari, Helsinki (Espoo), Finland on September 26-27, 2024. The meeting was jointly organised by the Scandinavian Neuropathological Society (chair Olivera Casar-Borota) and University of Helsinki. Drs.
View Article and Find Full Text PDFCircRNAs: A promising target for intervention regarding glycolysis in gastric cancer.
Heliyon
July 2024
The First Hospital of Lanzhou University, Lanzhou, China, 730000.
Gastric cancer is characterized by a high incidence and mortality rate, with therapeutic efficacy currently constrained by substantial limitations. Aerobic glycolysis in cancer constitutes a pivotal aspect of the reprogramming of energy metabolism in tumor cells and profoundly influences the malignant progression of cancer. CircRNAs, serving as stable endogenous RNA, have been shown to regulate downstream targets by sponging miRNAs, which in turn are involved in the regulation of multiple malignant behaviors in a variety of cancers through the CircRNA-miRNA axis, suggesting that CircRNAs could be used as potential therapeutic targets for cancer.
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