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Development of a machine learning predictive model for central venous catheter-associated thrombosis in patients undergoing abdominal surgery.
Nurs Crit Care
January 2025
Department of Nursing, the First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Background: Central venous catheters (CVCs) are placed where the vena cava meets the right atrium. Their common use raises the risk of catheter-related thrombosis (CRT), a potentially life-threatening complication.
Aim: This study leverages machine learning to develop a CRT predictive model for abdominal surgery patients, aiming to refine clinical decisions and elevate treatment quality.
Evaluation of Pregnancy Risks in Women with Subchorionic Hematoma Using Machine Learning Models.
Med Sci Monit
December 2024
Reproductive Center, Guangxi Medical University First Affiliated Hospital,, Nanning, Guangxi, China.
BACKGROUND Subchorionic hematoma (SCH) can lead to blood accumulation and potentially affect pregnancy outcomes. Despite being a relatively common finding in early pregnancy, the effects of SCH on pregnancy outcomes such as miscarriage, stillbirth, and preterm birth remain debated. This study aims to address these gaps by systematically evaluating the influence of SCH-related clinical factors on pregnancy outcomes using robust analytical techniques.
View Article and Find Full Text PDFThe factor XI/XIa antibody abelacimab combined with enoxaparin inhibits filter clotting in hemodialysis circuits ex vivo.
J Thromb Thrombolysis
December 2024
Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.
Drugs targeting factor XI may offer an alternative to heparin for preventing blood clotting in extracorporeal circulation. We investigated the effects of abelacimab, a novel monoclonal antibody targeting factor XI. We collected whole blood samples into two bags (each 240 ml, control group: enoxaparin 1.
View Article and Find Full Text PDFValidation of pathogen reduced plasmas from maxi-pools combined with fast thawing.
Transfus Med
December 2024
Department of Clinical Immunology and Transfusion Medicine, Uppsala University Hospital Blood Transfusion Center, Uppsala, Sweden.
Objectives: Fast thawing for emergency situations and reduction of plasma wastage.
Background: Evaluation of plasma units, pooled and pathogen reduced (PR) in "maxi-pools" with amotosalen and UVA light, and fast thawing.
Methods/materials: Per replicate, 10 WB-derived leukocyte depleted plasma units were frozen within 24 h at ≤ -25°C and stored for 7 days.
The effects of acidemia and acidemia reversal on coagulation in dogs.
Front Vet Sci
September 2024
College of Veterinary Medicine, Gyeongsang National University, Jinju, Republic of Korea.
Background: The effect of acidemia on blood coagulation remains inadequately understood in veterinary medicine. Therefore, we assessed the effect of acidification of canine whole blood on coagulation and investigated whether acidemia-induced coagulopathy could be reversed by reversing acidemia.
Methods: Citrated whole blood samples were taken from six healthy Beagle dogs and categorized, based on pH adjustment, into neutral, weak acidemia (WA), strong acidemia (SA), and reversal from SA.
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