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Berlin Heart EXCOR sVAD implantation technique for neonates and infants with functionally univentricular ductal-dependent systemic circulation.
Multimed Man Cardiothorac Surg
January 2025
Congenital Heart Center, Division of Cardiovascular Surgery, Department of Surgery, University of Florida, Gainesville, FL, USA.
The Berlin Heart EXCOR is a pulsatile paracorporeal ventricular assist device (VAD) for neonates, infants, children and adults with congenital or acquired severe ventricular dysfunction. Berlin Heart EXCOR VADs are routinely used as either a bridge to a cardiac transplantation, or occasionally as a bridge to ventricular recovery. Our programmatic philosophy is to bridge neonates and infants with functionally univentricular ductal-dependent systemic circulation or functionally univentricular ductal-dependent pulmonary circulation who are at high risk for staged palliation because of important cardiac risk factors with a single-ventricle VAD (sVAD) as a bridge to a cardiac transplant.
View Article and Find Full Text PDFRecent Developments in Ventricular Assist Device Therapy.
Rev Cardiovasc Med
January 2025
Center for Preclinical Surgical & Interventional Research, The Texas Heart Institute, Houston, TX 77030, USA.
The evolution of left ventricular assist devices (LVADs) from large, pulsatile systems to compact, continuous-flow pumps has significantly improved implantation outcomes and patient mobility. Minimally invasive surgical techniques have emerged that offer reduced morbidity and enhanced recovery for LVAD recipients. Innovations in wireless power transfer technologies aim to mitigate driveline-related complications, enhancing patient safety and quality of life.
View Article and Find Full Text PDFLong-term in vivo performance of silicone membrane lungs coated with novel methacryloyloxyethyl phosphorylcholine polymers: A pilot study.
Artif Organs
December 2024
Department of Bioengineering, The University of Tokyo Graduate School of Engineering, Tokyo, Japan.
Background: This study was designed to evaluate the long-term durability, oxygenation, and pressure loss of newly developed, methacryloyloxyethyl phosphorylcholine (MPC)-polymer-coated, nonporous silicone hollow fiber-membrane lungs in vivo using a pulmonary artery-to-left-atrium paracorporeal configuration.
Methods: An extracorporeal circuit from the pulmonary artery (device inflow) to the left atrium (device outflow) was established using dedicated composite vascular grafts in three healthy female goats for the prototype lung testing.
Results: Duration of testing the prototype lungs was 52, 57, or 100 days.
A Case of Cardiogenic Shock due to Propionic Acidemia-Associated Cardiomyopathy Successfully Treated with a Combination of Mechanical Circulatory Support and Medical Therapy.
Int Heart J
December 2024
Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University.
Article Synopsis
- An 18-year-old man with refractory cardiogenic shock from dilated cardiomyopathy was treated at the hospital through a paracorporeal left ventricular assist device (LVAD) implantation.
- Post-surgery, he experienced loss of consciousness and was diagnosed with propionic acidemia after further evaluations revealed metabolic issues and brain imaging findings.
- Following treatment for both his heart failure and propionic acidemia, his neurological and cardiac functions improved, leading to the successful removal of the LVAD; this case highlights the rare association between propionic acidemia and dilated cardiomyopathy in adults.
Different ECLS Pump Configurations for Temporary Right Ventricular Assist Device in LVAD Patients: A Retrospective Case-Control Study.
Life (Basel)
October 2024
Clinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Centre North Rhine Westphalia, 32545 Bad Oeynhausen, Germany.
Background: Acute right ventricular failure is a critical complication after left ventricular assist device (LVAD) implantation, often managed with a temporary paracorporeal right ventricular assist device (RVAD). This study examined three extracorporeal life support (ECLS) systems regarding mortality, bleeding complications, and intensive care unit (ICU) stay duration.
Methods: This monocentric, retrospective case-control study included all patients receiving LVAD with paracorporeal RVAD between 2009 and 2020.
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