Ectopic spiral wave sources were produced in pieces of 15 X 15 mm of rabbit atrium by an induction of a single properly timed premature impulse. The cycle length of the ectopic source (T) gradually increased immediately after its appearance. It was shown that T growth is determined by the rise of refractoriness (R). It was found that besides the well known phenomenon of R shortening after f increase there is an opposite process of R lengthening at high driving rates (f > 4--5 sec--1). A hypothesis is advanced that the growth of refractoriness found is one of the death mechanisms of spiral wave ectopic sources in the heart.
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Large-scale quantum photonic circuits require integrating multiple single-photon sources, which are typically based on spontaneous four-wave mixing (SFWM) in spiral waveguides or microring resonators (MRRs). Photons can be generated in both clockwise (CW) and counterclockwise (CCW) orientations from a single source in a Sagnac configuration, showing promise for improving scalability. In this work, we propose a fully integrable scheme for bidirectional creation and usage of single photons.
View Article and Find Full Text PDFSoft Matter
January 2025
Institute for Solid State Physics, University of Tokyo, Kashiwa, Chiba 277-8581, Japan.
Nonequilibrium membrane pattern formation is studied using meshless membrane simulation. We consider that molecules bind to either surface of a bilayer membrane and move to the opposite leaflet by flip-flop. When binding does not modify the membrane properties and the transfer rates among the three states are cyclically symmetric, the membrane exhibits spiral-wave and homogeneous-cycling modes at high and low binding rates, respectively, as in an off-lattice cyclic Potts model.
View Article and Find Full Text PDFJ Adolesc
January 2025
Institute of Psychology, University of Wroclaw, Wroclaw, Poland.
Introduction: Initial evidence suggests that engaging with accepting communities on social media such as Instagram may inform sexual minority youths' sense of stigma and well-being. However, as existing research has predominately drawn upon cross-sectional or qualitative designs, it is currently unclear whether the positive experiences identified in previous research accumulate, endure, or evolve over time. We also know relatively little about whether engagement with accepting online communities is primarily a compensatory or enhancing behavior.
View Article and Find Full Text PDFSci Adv
January 2025
Center for Nano Science and Technology, Fondazione Istituto Italiano di Tecnologia, Milano, Italy.
Achieving highly tailored control over both the spatial and temporal evolution of light's orbital angular momentum (OAM) on ultrafast timescales remains a critical challenge in photonics. Here, we introduce a method to modulate the OAM of light on a femtosecond scale by engineering a space-time coupling in ultrashort pulses. By linking azimuthal position with time, we implement an azimuthally varying Fourier transformation to dynamically alter light's spatial distribution in a fixed transverse plane.
View Article and Find Full Text PDFSci Rep
January 2025
Institute for Open and Transdisciplinary Research Initiatives, Osaka University, Yamadaoka 2-1, Suita, 565-0871, Osaka, Japan.
Heterogeneity is a critical determinant for multicellular pattern formation. Although the importance of microscale and macroscale heterogeneity at the single-cell and whole-system levels, respectively, has been well accepted, the presence and functions of mesoscale heterogeneity, such as cell clusters with distinct properties, have been poorly recognized. We investigated the biological importance of mesoscale heterogeneity in signal-relaying abilities (excitability) in the self-organization of spiral waves of intercellular communications by studying the self-organized pattern formation in a population of Dictyostelium discoideum cells, a classical signal-relaying system model.
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