Serum amyloid protein (SAA) levels were determined by radioimmunoassay in 90 children with juvenile rheumatoid arthritis (JRA). Significantly higher levels of SAA were present in children with the polyarticular and systemic forms of the disease. SAA levels correlate with disease activity, increasing during acute exacerbations, decreasing during remission and in patients having prednisone therapy. High serum SAA concentrations in children with JRA did not correlate with the presence of secondary amyloidosis and may be useful as a disease monitor.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1000521PMC
http://dx.doi.org/10.1136/ard.39.3.228DOI Listing

Publication Analysis

Top Keywords

serum amyloid
8
amyloid protein
8
rheumatoid arthritis
8
saa levels
8
levels
4
protein levels
4
levels south
4
south american
4
children
4
american children
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!