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Article Synopsis
  • A study in Germany found that nitroxoline is a recommended antibiotic for women with a type of urinary infection called acute uncomplicated cystitis (UC).
  • Female patients were treated with nitroxoline and their symptoms were checked over several weeks; most reported good results and were happy with the treatment.
  • All tested bacteria causing the infections were sensitive to nitroxoline, confirming it’s still a safe and effective choice for treatment.
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Uncomplicated Bacterial Community-Acquired Urinary Tract Infection in Adults.

Dtsch Arztebl Int

December 2017

Department of Urology and Pediatric Urology, St. Antonius Hospital Eschweiler, Academic Teaching Hospital of RWTH Aachen, Eschweiler; UroEvidence@Deutsche Gesellschaft für Urologie, Berlin; Pharmacy, Nuremberg Hospitals; Hematology/Oncology, Department of Internal Medicine C, Faculty of Medicine, University of Greifswald; Department of Care Research, Institute for Public Health and Nursing Care Research, University of Bremen; Department of Urology, Pediatric Urology and Andrology, University Hospital of Gießen and Marburg Ltd., Justus-Liebig University Gießen.

Background: Uncomplicated bacterial community-acquired urinary tract infection is among the more common infections in outpatient practice. The resistance level of pathogens has risen markedly. This S3 guideline contains recommendations based on current evidence for the rational use of anti - microbial agents and for the prevention of inappropriate use of certain classes of antibiotics and thus of the resulting drug resistance.

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[On the treatment of candiduria and nitroxoline sensitivity of Candida isolates].

Urologe A

May 2017

Chefarzt der Fachklinik Urologie, Kurpark-Klinik, Kurstr. 41-45, 61231, Bad Nauheim, Deutschland.

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[Nitroxoline - an option for the antibiotic treatment of urinary tract infections].

Urologe A

February 2017

MVZ Labor Limbach, Im Breitspiel 15, 69126, Heidelberg, Deutschland.

Background: Resistance of uropathogenic bacteria against the common antibiotics is considerable-especially in the elderly.

Objectives: In Germany nitroxoline is licensed for the treatment of acute urinary tract infections and for prophylaxis of recurrent infections. What is the actual resistance pattern of uropathogenic bacteria?

Materials And Methods: The in vitro susceptibility of 477 uropathogenic bacteria from patients in 2015 was determined by means of the agar diffusion method.

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There is lately observed an increase in the resistance of the main pathogens of urologic infection to β-lactam antibiotics due to production of plasmid-induced β-lactamases. The aim of the study was to reveal types TEM, SHV and CTX-M plasmid β-lactamases among uropathogens. Out of 115 isolates, 30 (26.

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