The authors studied the influence of the blood sera of 23 patients suffering from rheumatism on blast-transformation of lymphocytes obtained from healthy persons, in mixed cultures: 4 sera stimulated it, 5--depressed, and 14 produced no effect. Among patients whose sera depressed the blast-transformation persons with a more severe cardiovascular insufficiency prevailed. The content of IgG, IgM and alpha2-globulins in these sera was greater.

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