Antemortem diagnosis of amelanotic metastatic melanoma to jejunum was made in a 35-year-old white man, who is still alive and healthy. Electron microscopy, in addition to finding premelanosomes, revealed virus-like intranuclear inclusions. Nuclear pockets and junctions of endoplasmic reticulum were also observed.
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http://dx.doi.org/10.1177/030089168006600413 | DOI Listing |
J Vet Diagn Invest
December 2024
Zoological Health Program, Wildlife Conservation Society, Bronx Zoo, Bronx, NY, USA.
We identified a novel herpesvirus in 2 deceased captive blue penguins (). Moderate-to-severe myocardiocyte atrophy and necrosis, and eosinophilic intranuclear inclusion bodies (INIBs), were seen in myocardiocytes in one bird; reticuloendothelial (RE) cell INIBs and multifocal RE cell necrosis were seen in both birds. The histologic findings were suggestive of viral infection.
View Article and Find Full Text PDFBMC Neurol
December 2024
Department of Neurology, Peking University Shenzhen Hospital, Shenzhen, Guangdong, 518036, China.
Neuronal intranuclear inclusion disease (NIID) is a rare progressive neurodegenerative disease with a characteristic pathological feature of eosinophilic hyaluronan inclusions in the nervous system and internal organs. The identification of GGC-repeat expansions in the Notch 2 N-terminal like C (NOTCH2NLC) gene facilitates the accurate diagnosis of NIID. Due to its rareness and high clinical heterogeneity, the diagnosis of NIID is often delayed or missed.
View Article and Find Full Text PDFFront Microbiol
November 2024
Department of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh.
Background: Fowl adenovirus (FAdV) is a globally distributed virus that inflicts significant economic losses on the poultry industry. The study aimed at pathological investigation, molecular characterization, isolation, and pathogenicity determination of FAdV from commercial poultry.
Methods: A total of 86 liver samples were collected from 80 commercial chicken farms.
Mol Neurodegener
November 2024
Neural Stem Cell Research Lab, Research Department, National Neuroscience Institute, Singapore, 308433, Singapore.
J Adv Vet Anim Res
September 2024
Department of Pathology, Bangladesh Agricultural University, Mymensingh, Bangladesh.
Objective: The purpose of this study was to characterize the circulating Peste des Petits Ruminants virus (PPRV) from slaughtered goats and conduct a phylogenetic analysis of the N gene of PPRV.
Materials And Methods: A total of 196 slaughtered goats were investigated at the marketplaces of Mymensingh division from January 2019 to March 2021. Lungs, spleen, and mesenteric lymph nodes were collected for histology and molecular study.
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