The effect of spaceflight simulation factors (ascent to an altitude of 8,000 m, anticipation of centrifugation, psychological test, hypokinesia, and enclosure in an altitude chamber) on the content of free and protein-bound 11-hydroxycorticosteroids in plasma was studied. This exposure produced changes in the total and fractional content of the hormones. The changes depended on the simulation factor, duration of its action, and functional status of test subjects.

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