The authors conducted a repeated examination of 150 patients suffering from ischemic heart disease with normolipidemia and types IIa, IIb and IV hyperlipoproteinemia. The content of alpha-cholesterol in these patients tended to fluctuate, just as the content of other blood lipid fractions. Its fluctuations were most marked in types 11b and IV hyperlipoproteinemia. Comparison of the alpha-cholesterol content in patients with ischemic heart disease with the results of population tests confirmed the information on its lower level in patients. A still greater difference between patients and healthy individuals was revealed when the percentage of total cholesterol for which alpha-lipoproteines accounted and the value of the cholesterol atherogenic index were compared. Reduced concentration of alpha-cholesterol was encountered not only in hyperlipoproteinemia, but also in normolipidemia. The level of alpha-cholesterol had a negative correlative connection with the content of triglycerides in the blood.
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