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Leukemia is one of the most common cancers in prepubertal girls and adolescents, with advances improving survival rates. However, treatments like chemotherapy and radiation are highly gonadotoxic, often causing ovarian insufficiency, early menopause, infertility, and endocrine disorders. Fertility preservation for young female cancer patients, especially prepubertal girls without mature germ cells, relies heavily on ovarian tissue cryopreservation.

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Effect of UV exposure on DNA deposited on drug capsules.

Forensic Sci Int

January 2025

College of Science and Engineering, Flinders University, Bedford Park, South Australia 5042, Australia.

Illicit drugs are often made in less-than-sterile environments and can be stored in ways which can be detrimental to any DNA present, such as whether they are exposed to UV radiation. Previously, analysis of how exposure to UV impacted DNA for forensic applications has been in controlled laboratory conditions isolating a single component of UV radiation and often on DNA-rich samples such as bloodstains or saliva. To evaluate DNA persistence in more realistic conditions, capsules, such as those used to distribute controlled substances, were manually made and then packed into ziplock bags.

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Near-infrared light reflection for the early detection of proximal caries in posterior teeth: an in vivo study.

BMC Oral Health

January 2025

Center for Plastic & Reconstructive Surgery, Department of Stomatology, Affiliated People's Hospital, Zhejiang Provincial People's Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China.

Background: The purpose of this study was to evaluate the validity of near-infrared light reflection for detecting different depths of proximal caries in posterior teeth and to compare it with commonly used clinical oral examinations and bitewing radiography images.

Methods: Twenty-six patients with a total of 516 proximal surfaces were included in this study. The ground truth of the proximal caries was determined through a consensus reached by two experienced dentists after an intraoral examination assisted by bitewing radiographs.

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The effectiveness of ultraviolet-C light-emitting diodes (UVC LEDs) is currently limited by the lack of suitable encapsulation materials, restricting their use in sterilization, communication, and in vivo cancer tumor inhibition. This study evaluates various silicone oils for UVC LED encapsulation. A material aging experiment was conducted on CF1040 (octamethylcyclotetrasiloxane), HF2020 (methyl hydro polysiloxanes), and MF2020-1000 (polydimethylsiloxane) under UVC radiation for 1000 h.

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The melon fly, , poses a severe threat to the country's agricultural productivity, particularly in the cultivation of cucurbitaceous crops. This study was conducted to determine the ideal irradiation dose to be used to set up a Sterile Insect Technique (SIT)-based strategy to control outbreaks in Sri Lanka. A colony was established and maintained under standard laboratory conditions.

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