AI Article Synopsis

  • The use of 15N as a tracer in medical research is growing in importance, particularly since 1965, through collaborations between surgeons and isotope researchers.
  • A variety of test models were employed in these studies, including different methods of administering 15N-labelled substances to subjects such as healthy individuals, stressed patients, and test animals after gastric surgeries.
  • The research demonstrates the potential for mathematical models to be utilized in analyzing the data obtained from these studies.

Article Abstract

The importance of 15N as tracer in medical research is increasing. Since 1965 many results were obtained in cooperation of surgeons (Surgical clinic of Karl-Marx-University; Bezirkskrankenhaus St. Georg, Leipzig) and coworkers of Central Institute of Isotope and Radiation research. Using 3 test models (15N-labelled amino acid solution, permanent infused; 15N-labelled glycine, given as one single dose; 15N-labelled casein, oral given) healthy persons, patients in stress condition and after gastric operations and rats after performing several types of gastric operations were studied. Possibilities of calculations with mathematical models are shown.

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