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The present study examined the effect of the three different altitudes on the enzymatic activity and the prokaryotic communities of the rhizosphere of (L.) A.DC.

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Approximately 64% of the Republic of Korea comprises mountainous areas, which as cold and high-altitude regions are gravely affected by climate change. Within the mountainous and the alpine-subalpine ecosystems, microbial communities play a pivotal role in biogeochemical cycling and partly regulate climate change through such cycles. We investigated the composition and function of microbial communities, with a focus on fungal communities, in Republic of Korea's second tallest mountain, Mt.

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Introduction: The grayling ( L.) has several advantages over other fish species that make it attractive for aquaculture and invest it with importance for food security. The study assessed the effects of a β-glucan-enriched diet on biomarkers of oxidative stress, energy metabolism and lysosomal function in muscle tissue of European grayling ( L.

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A Drosophila Model of Mucopolysaccharidosis IIIB.

Genetics

December 2024

Department of Genetics and Biochemistry and Center for Human Genetics, Clemson University, 114 Gregor Mendel Circle, Greenwood, SC 29646, USA.

Article Synopsis
  • MPS IIIB is a rare disorder caused by defects in the enzyme NAGLU, leading to brain dysfunction due to the accumulation of heparan sulfate in lysosomes.
  • Researchers created a Drosophila (fruit fly) model with various NAGLU mutations to study the disorder's effects on activity and sleep patterns, revealing significant hyperactivity and sleep issues.
  • The study found that gene expression changes in mutant flies are linked to problems with nervous system development and synaptic function, suggesting that this fly model could help develop future therapies for MPS IIIB.
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Anthropogenic nitrogen (N) deposition is unequally distributed across space and time, with inputs to terrestrial ecosystems impacted by industry regulations and variations in human activity. Soil carbon (C) content normally controls the fraction of mineralized N that is nitrified (ƒ), affecting N bioavailability for plants and microbes. However, it is unknown whether N deposition has modified the relationships among soil C, net N mineralization, and net nitrification.

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